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Human IL-11 ELISA Kit is a Sandwich (quantitative) ELISA kit for the measurement of Human IL-11 in Human in Plasma, Tissue Homogenate, Serum samples.

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Images

Sandwich ELISA - Human IL-11 ELISA Kit (AB285297), expandable thumbnail

Key facts

Detection method
Colorimetric
Sample types
Plasma, Tissue Homogenate, Serum
Assay type
Sandwich (quantitative)
Reactive species
Human
Range
31.25 - 2000 pg/mL
Sensitivity
< 18.75 pg/mL

Reactivity data

Application
sELISA
Reactivity
Reacts
Dilution info
-
Notes

-

Target data

Function

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed:30279168).

Alternative names

What's included?

96 Test
Components
25X Wash buffer
1 x 30 mL
Antibody dilution buffer
1 x 10 mL
Biotin/Detection antibody (Concentrated)
1 x 120 µL
HRP-Streptavidin Conjugate (SABC)
1 x 120 µL
Lyophilized Standard
2 x 1 Vial
Micro ELISA Plate
1 x 1 Unit
Plate sealers
5 x 1 Unit
SABC dilution buffer
1 x 10 mL
Sample and Standard Dilution Buffer
1 x 20 mL
Stop Solution
1 x 10 mL
TMB Substrate
1 x 10 mL

Recommended products

Human IL-11 ELISA Kit is a Sandwich (quantitative) ELISA kit for the measurement of Human IL-11 in Human in Plasma, Tissue Homogenate, Serum samples.

Key facts

Detection method
Colorimetric
Sample types
Plasma, Tissue Homogenate, Serum
Assay type
Sandwich (quantitative)
Reactive species
Human
Range
31.25 - 2000 pg/mL
Assay Platform
Microplate (12 x 8 well strips)
Sensitivity
< 18.75 pg/mL

Precision

Intra assay

Sample
Overall
n
0
mean
-
SD
-
C.V.
< 8

Inter assay

Sample
Overall
n
0
mean
-
SD
-
C.V.
< 10

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
+4°C

Notes

This IL-11 ELISA kit (ab285297, E4283) is a sandwich ELISA assay for the quantitative measurement of human IL-9 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of human IL-11 captured from the samples.

This product is manufactured by BioVision, an Abcam company and was previously called E4283 IL-11 (Human) ELISA Kit. E4283-100 is the same size as the 96 test size of ab285297.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Sandwich ELISA - Human IL-11 ELISA Kit (ab285297), expandable thumbnail

    Sandwich ELISA - Human IL-11 ELISA Kit (ab285297)

    Human IL-11 ELISA Kit.

    Typical Standard Curve: These standard curves are for demonstration only. A standard curve must be run with each assay.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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