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AB108746

Human Anti-Influenza virus B IgG ELISA Kit

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(2 Publications)

Human Anti-Influenza virus B IgG ELISA Kit is an indirect ELISA for the qualitative detection of IgG class antibodies against Influenza virus B in human plasma and serum samples.

- Colorimetric readout - 450 nm - Works on any standard plate reader
- Easy results interpretation
- Cut-off, positive and negative controls included

Key facts

Detection method

Colorimetric

Sample types

Citrate plasma, Heparin Plasma, Serum

Reacts with

Human

Assay type

Indirect

Assay Platform

Microplate

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Abcam's anti-Influenza virus B IgG Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the accurate qualitative measurement of IgG class antibodies against Influenza virus B in Human serum and plasma.

A 96-well plate has been precoated with Influenza virus B antigens to bind cognate antibodies. Controls or test samples are added to the wells and incubated. Following washing, a horseradish peroxidase (HRP) labelled anti-Human IgG conjugate is added to the wells, which binds to the immobilized Influenza virus B-specific antibodies. TMB is then catalyzed by the HRP to produce a blue color product that changes to yellow after adding an acidic stop solution. The density of yellow coloration is directly proportional to the amount of Influenza virus B IgG sample captured in plate.

REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

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Precision

[ { "reproducibilityType": "Inter", "sample": "Serum", "replicates": 20, "mean": null, "standardDeviation": null, "coefficientOfVariability": "3.2" }, { "reproducibilityType": "Intra", "sample": "Serum", "replicates": 8, "mean": null, "standardDeviation": null, "coefficientOfVariability": "3.4" } ]
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What's included?

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab108746-1x96Tests", "assetComponentDetails": [ { "size":"1 x 20 mL", "name":"Influenza virus B anti-IgG HRP Conjugate", "number":"AB108746-CMP09", "productcode":"" }, { "size":"1 x 2 mL", "name":"Influenza virus B IgG Positive Control", "number":"AB108746-CMP10", "productcode":"" }, { "size":"1 x 3 mL", "name":"Influenza virus B IgG Cut-off Control", "number":"AB108746-CMP06", "productcode":"" }, { "size":"1 x 2 mL", "name":"Influenza virus B IgG Negative Control", "number":"AB108746-CMP07", "productcode":"" }, { "size":"1 x 100 mL", "name":"IgG Sample Diluent", "number":"AB108746-CMP01", "productcode":"" }, { "size":"1 x 50 mL", "name":"20X Washing Solution", "number":"AB108746-CMP05", "productcode":"" }, { "size":"1 x 15 mL", "name":"Stop Solution", "number":"AB108746-CMP11", "productcode":"" }, { "size":"1 x 15 mL", "name":"TMB Substrate Solution", "number":"AB108746-CMP04", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Strip holder", "number":"AB108746-CMP02", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Cover foil", "number":"AB108746-CMP03", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Influenza virus B (IgG) Coated Microplate (12 x 8 wells)", "number":"AB108746-CMP08", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
+4°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Influenza B IgG also referred to as Flu B Antibodies are immunoglobulins targeting the Influenza B virus which is one of the two main types of influenza viruses that cause human flu epidemics. Influenza B viruses have a slower mutation rate compared to Influenza A but they can still cause significant seasonal outbreaks. These antibodies play an essential role in neutralizing the virus and curbing infection. They are expressed in the serum of individuals following infection or vaccination and their levels can be measured using techniques like ELISA test kits specifically designed for Influenza B antibody detection. The molecular mass of a typical IgG molecule is approximately 150 kDa.
Biological function summary

These antibodies are critical for the immune defense mechanism against the Influenza B virus. They are part of the larger immunoglobulin complex which is responsible for identifying and immobilizing pathogens. IgG antibodies against Influenza B target viral surface proteins such as hemagglutinin (HA) and neuraminidase (NA) which are essential for the virus's ability to infect host cells. This action assists in the prevention of the virus entering cells and propagating within the host.

Pathways

IgG antibodies against Influenza B are integral to the adaptive immune response. The antibodies function within the humoral immunity pathway working alongside proteins like B cell receptors and helper T cells to generate a specific response against the virus. This response is important for long-term immune memory and protection against future Influenza B infections. Interactions with proteins involved in the antigen presentation pathway are also noteworthy as they enhance the immune system's ability to target the Influenza B virus effectively.

IgG antibodies provide significant defense against influenza infections particularly those caused by the Influenza B virus. These influenza-related illnesses are characterized by symptoms such as fever cough sore throat and fatigue. The presence and efficacy of Influenza B IgG are vital for reducing the severity and duration of these symptoms. In some cases individuals with compromised immune systems show lower levels of these antibodies predisposing them to more severe influenza-related complications. The connection between influenza B IgG levels and proteins involved in immune deficiencies highlights the importance of robust antibody responses for effective disease prevention and management.
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Product protocols

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Target data

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in nutrition 10:1116634 PubMed37168053

2023

Healthy adults supplemented with a nutraceutical formulation containing gel, rosemary and enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial.

Applications

Unspecified application

Species

Unspecified reactive species

Erin D Lewis,David C Crowley,Najla Guthrie,Malkanthi Evans

Vaccines 10: PubMed35891309

2022

Adults with Trisomy 21 Have Differential Antibody Responses to Influenza A.

Applications

Unspecified application

Species

Unspecified reactive species

Stephanie James,Robert C Haight,Cassandra Hanna,Lindsey Furton
View all publications
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websiteProtocolBooklet
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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