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AB313503

Human INHBC ELISA Kit

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Human INHBC ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human INHBC in Human in Cell Culture Media, Biofluids samples.

View Alternative Names

Inhibin beta C chain, Activin beta-C chain, INHBC

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Sandwich ELISA - Human INHBC ELISA Kit (AB313503)
  • sELISA

Supplier Data

Sandwich ELISA - Human INHBC ELISA Kit (AB313503)

Example of standard curve using ab313503. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.

Key facts

Detection method

Colorimetric

Sample types

Cell culture supernatant, Plasma, Serum

Reacts with

Human

Assay type

Sandwich (quantitative)

Sensitivity

= 0.1 ng/mL

Assay Platform

Pre-coated microplate (12 x 8 well strips)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Human INHBC ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human INHBC in serum, plasma and cell culture supernatants. This assay employs an antibody specific for human INHBC coated on a 96-well plate.
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Recovery

[ { "sample": "Cell culture media", "range": "95 - 103 %", "average": "= 101.7" }, { "sample": "Plasma", "range": "89 - 103 %", "average": "= 97.28" }, { "sample": "Serum", "range": "89 - 142 %", "average": "= 107.4" } ]
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What's included?

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab313503-1x96Tests", "assetComponentDetails": [ { "size":"1 x 25 mL", "name":"20X Wash Buffer", "number":"AB313503-CMP04", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Human INHBC Antibody-coated ELISA Plate", "number":"AB313503-CMP08", "productcode":"" }, { "size":"1 x 8 mL", "name":"Stop Solution; 0.2M Sulfuric Acid", "number":"AB313503-CMP06", "productcode":"" }, { "size":"1 x 200 µL", "name":"200X HRP-Streptavidin", "number":"AB313503-CMP03", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Biotinylated Human INHBC Detection Antibody", "number":"AB313503-CMP09", "productcode":"" }, { "size":"1 x 12 mL", "name":"TMB One-Step Substrate Reagent", "number":"AB313503-CMP07", "productcode":"" }, { "size":"1 x 15 mL", "name":"5X Assay Diluent (Item E2)", "number":"AB313503-CMP05", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Lyophilized Human INHBC Protein Standard", "number":"AB313503-CMP10", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

INHBC also known as Inhibin Beta C is a protein known for its role in various cellular processes. It has a molecular mass of approximately 42 kDa. This protein expresses in a variety of tissues including liver testis and ovary. INHBC belongs to the transforming growth factor-beta (TGF-beta) superfamily known for its involvement in cell growth and differentiation.
Biological function summary

INHBC functions as part of the Inhibin/Activin complex that regulates follicle-stimulating hormone (FSH) secretion. Activin which INHBC is a subunit of plays a role in reproductive processes and cellular differentiation. This protein actively participates in modulating processes related to gonadal functions and embryogenesis. Its activity impacts cell proliferation anti-inflammatory responses and wound healing.

Pathways

INHBC interplays within the TGF-beta signaling pathway an important pathway controlling cellular proliferation and differentiation. It relates closely to Inhibin Alpha and Activin A within these pathways. These interactions with related proteins allow it to influence reproductive and cellular growth processes and maintain regulatory balances in physiology.

INHBC correlates with conditions such as reproductive system disorders and certain cancers. Its overexpression or dysregulation can link to ovarian cancer through its association with Activin A. Research suggests that alterations in INHBC levels may influence pathological conditions by disturbing normal growth factor signaling emphasizing its role in disease progression.
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Product protocols

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Target data

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
See full target information Inhibin beta C chain
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websiteProtocolBooklet
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