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Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Human LTBP2 ELISA Kit is a Sandwich (quantitative) ELISA kit for the measurement of Human LTBP2 in Human in Serum, Plasma, Cell culture supernatant samples.
Colorimetric
Serum, Plasma, Cell culture supernatant
Sandwich (quantitative)
Human
17.5 - 5000 pg/mL
= 17.5 pg/mL
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application sELISA | Reactivity Reacts | Dilution info - | Notes - |
May play an integral structural role in elastic-fiber architectural organization and/or assembly.
Latent-transforming growth factor beta-binding protein 2, LTBP-2, LTBP2, C14orf141, LTBP3
Human LTBP2 ELISA Kit is a Sandwich (quantitative) ELISA kit for the measurement of Human LTBP2 in Human in Serum, Plasma, Cell culture supernatant samples.
Latent-transforming growth factor beta-binding protein 2, LTBP-2, LTBP2, C14orf141, LTBP3
Colorimetric
Serum, Plasma, Cell culture supernatant
Sandwich (quantitative)
Human
17.5 - 5000 pg/mL
Pre-coated microplate (12 x 8 well strips)
= 17.5 pg/mL
Sample type | Average % | Range |
---|---|---|
Sample type Serum | Average % = 112.5 | Range 101 - 123 % |
Sample type Plasma | Average % = 107.3 | Range 98 - 120 % |
Sample type Cell culture media | Average % = 100.4 | Range 93 - 105 % |
Blue Ice
-20°C
-20°C
Human LTBP2 ELISA Kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human LTBP2 in serum, plasma and cell culture supernatants. This assay employs an antibody specific for human LTBP2 coated on a 96-well plate.
LTBP2 interacts with the extracellular matrix components and acts as a structural protein. LTBP2 is an important part of TGF-β complexes. By anchoring TGF-β in a latent form it controls the availability and activation of TGF-β which is necessary for processes like cell growth differentiation and tissue repair. Without LTBP2 the controlled release of TGF-β can be disrupted impacting various cell functions.
LTBP2 also known as latent transforming growth factor-beta binding protein 2 is a glycoprotein involved in the regulation of transforming growth factor-beta (TGF-β) signaling. This protein has a mass of approximately 195 kDa. LTBP2 is expressed in a variety of tissues including the lungs heart and eyes. It plays an important role in the extracellular matrix where it is fundamental to the sequestration and subsequent activation of TGF-β.
LTBP2 regulates the TGF-β signaling pathway and maintains its equilibrium. This regulatory function links LTBP2 to the pathways involving cell proliferation and differentiation. LTBP2 closely interacts with other members of the LTBP family as well as proteins like fibrillin which are involved in the structural integrity of the extracellular matrix. These interactions are significant for maintaining proper signal transduction and cellular responses.
LTBP2 mutations have associations with conditions such as glaucoma and Weill-Marchesani syndrome. In glaucoma abnormalities in LTBP2 might affect the integrity of the extracellular matrix influencing intraocular pressure regulation. It also connects to fibrillin-related disorders due to its interaction with fibrillin proteins. These associations highlight the importance of LTBP2 in both structural and signaling roles within the body.
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Terms & Conditions.
Example of standard curve using ab313988. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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