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AB314384

Human S100A7 ELISA Kit

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Human S100A7 ELISA Kit is a Sandwich ELISA for the measurement of Human S100A7 in Human in Biofluids, Cell Culture Media samples.

View Alternative Names

PSOR1, S100A7C, S100A7, Protein S100-A7, Psoriasin, S100 calcium-binding protein A7

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Sandwich ELISA - Human S100A7 ELISA Kit (AB314384)
  • sELISA

Supplier Data

Sandwich ELISA - Human S100A7 ELISA Kit (AB314384)

Example of standard curve using ab314384. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.

Key facts

Detection method

Colorimetric

Sample types

Serum, Plasma, Cell culture supernatant

Reacts with

Human

Assay type

Sandwich

Results type

Quantitative

Sensitivity

= 24 pg/mL

Range

24 - 6000 pg/mL

Assay Platform

Pre-coated microplate (12 x 8 well strips)

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Complementary Products

Primary Antibodies

AB275040

Anti-Psoriasin antibody [EPR23482-38] - BSA and Azide free

BOND RX™ Validated|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-Psoriasin antibody [EPR23482-38] - BSA and Azide free (AB275040)

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Proteins & Peptides

AB105577

Recombinant Human Psoriasin protein (His tag N-Terminus)

Western blot - Recombinant Human Psoriasin protein (His tag N-Terminus) (AB105577)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Human S100A7 ELISA Kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human S100A7 in serum, plasma and cell culture supernatants. This assay employs an antibody specific for human S100A7 coated on a 96-well plate.
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Recovery

[ { "sample": "Serum", "range": "136 - 147 %", "average": "= 142" }, { "sample": "Plasma", "range": "80 - 148 %", "average": "= 123.6" }, { "sample": "Cell culture media", "range": "136 - 148 %", "average": "= 143.4" } ]
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What's included?

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab314384-1x96Tests", "assetComponentDetails": [ { "size":"2 x 1 Vial", "name":"Lyophilized Human S100A7 Protein Standard", "number":"AB314384-CMP10", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Human S100A7 Antibody-coated ELISA Plate", "number":"AB314384-CMP08", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Biotinylated Human S100A7 Detection Antibody", "number":"AB314384-CMP09", "productcode":"" }, { "size":"1 x 200 µL", "name":"200X HRP-Streptavidin", "number":"AB314384-CMP03", "productcode":"" }, { "size":"1 x 25 mL", "name":"20X Wash Buffer", "number":"AB314384-CMP04", "productcode":"" }, { "size":"1 x 15 mL", "name":"5X Assay Diluent (Item E2)", "number":"AB314384-CMP05", "productcode":"" }, { "size":"1 x 8 mL", "name":"Stop Solution; 0.2M Sulfuric Acid", "number":"AB314384-CMP06", "productcode":"" }, { "size":"1 x 12 mL", "name":"TMB One-Step Substrate Reagent", "number":"AB314384-CMP07", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Psoriasin also known as S100A7 is a member of the S100 protein family. It has a molecular mass of approximately 11.4 kDa. This protein exhibits calcium binding properties that influence its function. Psoriasin primarily expresses in keratinocytes which are predominant in the epidermis of the skin. Additionally it appears in various epithelia like mucous membranes. The expression levels rise in certain skin conditions suggesting it has a role in skin physiology.
Biological function summary

Psoriasin acts as an antimicrobial peptide contributing to the skin’s defense system against microbial invasion. It helps in controlling the growth of bacteria like E. coli and fungi. The protein does not function as part of a larger complex. Instead it operates independently to maintain the integrity of the skin barrier. Psoriasin also shows involvement in the inflammatory response of the skin where it interact with other immune system players.

Pathways

Several biological systems involve psoriasin including inflammation and skin homeostasis pathways. It interacts closely with other S100 proteins such as S100A8 and S100A9 which are part of the inflammatory process. These interactions can regulate immune cell migration and cytokine production highlighting its active role in modulating skin immune responses. Psoriasin serves as an important component in maintaining the balance between immune protection and inflammation within these pathways.

Psoriasin associates with psoriasis and breast cancer. In psoriasis it significantly increases aligning with its role in inflammation and skin barrier maintenance. The upregulation of psoriasin in psoriasis has been linked to overexpression of related proteins like S100A8 contributing to the chronic inflammatory state. In breast cancer particularly in certain carcinoma contexts its presence suggests a role in cancer cell survival. Researchers study its interaction with proteins in the cancer microenvironment to better understand its influence on tumor progression.
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Product protocols

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Target data

See full target information S100A7
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websiteProtocolBooklet
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Product promise

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For full details, please see our Terms & Conditions

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