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AB108904

Human Tissue Factor Pathway Inhibitor ELISA Kit (TFPI)

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(6 Publications)

Human Tissue Factor Pathway Inhibitor ELISA Kit (TFPI) is a Sandwich (quantitative) ELISA for the measurement of Human Tissue Factor Pathway Inhibitor (TFPI) in Human in Biofluids samples.

View Alternative Names

LACI, TFPI1, TFPI, Tissue factor pathway inhibitor, Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, EPI

2 Images
Sandwich ELISA - Human Tissue Factor Pathway Inhibitor ELISA Kit (TFPI) (AB108904)
  • sELISA

Lab

Sandwich ELISA - Human Tissue Factor Pathway Inhibitor ELISA Kit (TFPI) (AB108904)

TFPI measured in various samples showing quantity (ng) per mL of tested sample

Sandwich ELISA - Human Tissue Factor Pathway Inhibitor ELISA Kit (TFPI) (AB108904)
  • sELISA

Supplier Data

Sandwich ELISA - Human Tissue Factor Pathway Inhibitor ELISA Kit (TFPI) (AB108904)

Representative Standard Curve using ab108904.

Key facts

Detection method

Colorimetric

Sample types

Plasma, Milk, Serum, Cerebral Spinal Fluid

Reacts with

Human

Assay type

Sandwich (quantitative)

Sensitivity

> 52 pg/mL

Range

0.625 - 5 ng/mL

Assay time

5h

Assay Platform

Microplate

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Product details

Abcam's Tissue Factor Pathway Inhibitor (TFPI) Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of Tissue Factor Pathway Inhibitor concentrations in plasma, serum, milk, cerebrospinal fluid and cell culture samples.

A Tissue Factor Pathway Inhibitor specific antibody has been precoated onto 96-well plates and blocked. Standards or test samples are added to the wells and subsequently a Tissue Factor Pathway Inhibitor specific biotinylated detection antibody is added and then followed by washing with wash buffer. Streptavidin-Peroxidase Conjugate is added and unbound conjugates are washed away with wash buffer. TMB is then used to visualize Streptavidin-Peroxidase enzymatic reaction. TMB is catalyzed by Streptavidin-Peroxidase to produce a blue color product that changes into yellow after adding acidic stop solution. The density of yellow coloration is directly proportional to the amount of Tissue Factor Pathway Inhibitor captured in plate.

Get results in 90 minutes with Human Tissue Factor Pathway Inhibitor ELISA Kit (ab188392) from our SimpleStep ELISA® range.

The entire kit may be stored at -20°C for long term storage before reconstitution - Avoid repeated freeze-thaw cycles.

Precision

[ { "reproducibilityType": "Inter", "sample": "Overall", "replicates": 0, "mean": null, "standardDeviation": null, "coefficientOfVariability": "10.4" }, { "reproducibilityType": "Intra", "sample": "Overall", "replicates": 0, "mean": null, "standardDeviation": null, "coefficientOfVariability": "3.5" } ]

What's included?

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
Multi
Storage information
Please refer to protocols

Product protocols

Target data

Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
See full target information TFPI

Publications (6)

Recent publications for all applications. Explore the full list and refine your search

FEBS open bio 10:1568-1576 PubMed32533762

2020

Transthyretin increases migration and invasion of rat placental trophoblast cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao-Peng Ma,Chong-Dong Liu,Guang-Ming Cao,Zhen-Yu Zhang

Drug design, development and therapy 12:575-582 PubMed29593380

2018

Bioequivalence of a biosimilar enoxaparin sodium to Clexane after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers.

Applications

Unspecified application

Species

Unspecified reactive species

Javier Martínez González,Mayte Monreal,Ignacio Ayani Almagia,Jordi Llaudó Garín,Lourdes Ochoa Díaz de Monasterioguren,Ibón Gutierro Adúriz

Thrombosis and haemostasis 117:238-245 PubMed27853809

2016

Single-dose ciraparantag safely and completely reverses anticoagulant effects of edoxaban.

Applications

Unspecified application

Species

Unspecified reactive species

Jack E Ansell,Sasha H Bakhru,Bryan E Laulicht,Solomon S Steiner,Michael A Grosso,Karen Brown,Victor Dishy,Hans J Lanz,Michele F Mercuri,Robert J Noveck,James C Costin

PLoS neglected tropical diseases 10:e0004713 PubMed27167223

2016

Modulation of Hemostatic and Inflammatory Responses by Leptospira Spp.

Applications

Unspecified application

Species

Unspecified reactive species

Mônica L Vieira,Clément Naudin,Matthias Mörgelin,Eliete C Romero,Ana Lucia T O Nascimento,Heiko Herwald

Molecular vision 22:424-35 PubMed27168718

2016

Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Ahmed M Abu El-Asrar,Mohammad Mairaj Siddiquei,Mohd Imtiaz Nawaz,Gert De Hertogh,Ghulam Mohammad,Kaiser Alam,Ahmed Mousa,Ghislain Opdenakker

Clinical journal of the American Society of Nephrology : CJASN 10:443-51 PubMed25542906

2014

Biomarkers of kidney injury and klotho in patients with atherosclerotic renovascular disease.

Applications

sELISA

Species

Human

Moo Yong Park,Sandra M Herrmann,Ahmed Saad,Alfonso Eirin,Hui Tang,Amir Lerman,Stephen C Textor,Lilach O Lerman
View all publications
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