Human uPA Receptor/U-PAR ELISA Kit (URKR) is a Sandwich (quantitative) ELISA kit for the measurement of Human uPA Receptor/U-PAR (URKR) in Human in Plasma, Tissue Extracts, Cell culture supernatant, Serum, Other biological fluids samples.
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- Oncology letters 21:4232021Prognostic significance of uPA and uPAR expression in patients with cervical cancer undergoing radiotherapy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDanupon Nantajit,Piyawan Chailapakul,Sarinya Bawornpatarapakorn,Sasikarn Chamchod,Kanyanee LaebuaPubMed 33850564
- Clinical and experimental pharmacology & physiology 47:1705-17122020SuPAR, a potential inflammatory mediator in psoriasis pathogenesis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLamiaa Hamie,Edward Eid,Ossama Abbas,Remi Safi,Tarak Nammour,Hani Tamim,Maha Makki,Carla Stephan,Divina Hasbani,Hisham Wehbe,Nohra Ghaoui,Mariana Hawa,Nourhan Nasser,Assaad Eid,Abdul-Ghani Kibbi,Mazen KurbanPubMed 32558953
Key facts
- Detection method
- Colorimetric
- Sample types
- Plasma, Tissue Extracts, Cell culture supernatant, Serum, Other biological fluids
- Assay type
- Sandwich (quantitative)
- Reactive species
- Human
- Range
- 62.5 - 4000 pg/mL
- Sensitivity
- < 4 pg/mL
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application sELISA | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Acts as a receptor for urokinase plasminogen activator (PubMed:15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Alternative names
CD87, MO3, UPAR, PLAUR, Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3
What's included?
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Human uPA Receptor/U-PAR ELISA Kit (URKR) is a Sandwich (quantitative) ELISA kit for the measurement of Human uPA Receptor/U-PAR (URKR) in Human in Plasma, Tissue Extracts, Cell culture supernatant, Serum, Other biological fluids samples.
Key facts
- Detection method
- Colorimetric
- Sample types
- Plasma, Tissue Extracts, Cell culture supernatant, Serum, Other biological fluids
- Assay type
- Sandwich (quantitative)
- Reactive species
- Human
- Range
- 62.5 - 4000 pg/mL
- Assay Platform
- Microplate
- Sensitivity
- < 4 pg/mL
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- -20°C
Notes
Abcam's Human uPA Receptor/U-PAR(URKR) in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the accurate quantitative measurement of Human uPA Receptor/U-PAR(URKR) in cell culture supernatants, serum, plasma (heparin, EDTA) and urine.
A uPA Receptor/U-PAR (URKR) specific mouse monoclonal antibody has been precoated onto 96-well plates. Standards and test samples are added to the wells and incubated. A biotinylated detection polyclonal antibody from goat specific for uPA Receptor/U-PAR(URKR) is then added followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. TMB is then used to visualize the HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes into yellow after adding acidic stop solution. The density of yellow coloration is directly proportional to the Human uPA Receptor amount of sample captured in plate.
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1 product image
Sandwich ELISA - Human uPA Receptor/U-PAR ELISA Kit (URKR) (ab119612)
Representative standard curve using ab119612
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Product protocols
- Visit the general protocols
- Visit troubleshooting
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