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AB119612

Human uPA Receptor/U-PAR ELISA Kit (URKR)

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(2 Publications)

Human uPA Receptor/U-PAR ELISA Kit (URKR) is a Sandwich (quantitative) ELISA for the measurement of Human uPA Receptor/U-PAR (URKR) in Human in Biofluids, Cell/Tissue Extracts, Cell Culture Media samples.

View Alternative Names

CD87, MO3, UPAR, PLAUR, Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3

1 Images
Sandwich ELISA - Human uPA Receptor/U-PAR ELISA Kit (URKR) (AB119612)
  • sELISA

Supplier Data

Sandwich ELISA - Human uPA Receptor/U-PAR ELISA Kit (URKR) (AB119612)

Representative standard curve using ab119612

Key facts

Detection method

Colorimetric

Sample types

Plasma, Tissue Extracts, Cell culture supernatant, Serum, Other biological fluids

Reacts with

Human

Assay type

Sandwich (quantitative)

Sensitivity

< 4 pg/mL

Range

62.5 - 4000 pg/mL

Assay Platform

Microplate

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Abcam's Human uPA Receptor/U-PAR (URKR) in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the accurate quantitative measurement of Human uPA Receptor/U-PAR (URKR) in cell culture supernatants, serum, plasma (heparin, EDTA) and urine.

A uPA Receptor/U-PAR (URKR) specific mouse monoclonal antibody has been precoated onto 96-well plates. Standards and test samples are added to the wells and incubated. A biotinylated detection polyclonal antibody from goat specific for uPA Receptor/U-PAR(URKR) is then added followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. TMB is then used to visualize the HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes into yellow after adding acidic stop solution. The density of yellow coloration is directly proportional to the Human uPA Receptor amount of sample captured in plate.

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What's included?

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
-20°C
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Product protocols

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Target data

Acts as a receptor for urokinase plasminogen activator (PubMed : 15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
See full target information PLAUR
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Oncology letters 21:423 PubMed33850564

2021

Prognostic significance of uPA and uPAR expression in patients with cervical cancer undergoing radiotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Danupon Nantajit,Piyawan Chailapakul,Sarinya Bawornpatarapakorn,Sasikarn Chamchod,Kanyanee Laebua

Clinical and experimental pharmacology & physiology 47:1705-1712 PubMed32558953

2020

SuPAR, a potential inflammatory mediator in psoriasis pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Lamiaa Hamie,Edward Eid,Ossama Abbas,Remi Safi,Tarak Nammour,Hani Tamim,Maha Makki,Carla Stephan,Divina Hasbani,Hisham Wehbe,Nohra Ghaoui,Mariana Hawa,Nourhan Nasser,Assaad Eid,Abdul-Ghani Kibbi,Mazen Kurban
View all publications
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