AB323819
Mouse INHBE ELISA Kit (Inhibin beta E)
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Mouse INHBE ELISA Kit (Inhibin beta E) is a ELISA for the measurement of Mouse INHBE (Inhibin beta E) in Mouse in Biofluids, Cell/Tissue Extracts samples.
View Alternative Names
Inhibin beta E chain, Activin beta-E chain
1 Images
- cELISA
Supplier Data
Competitive ELISA - Mouse INHBE ELISA Kit (Inhibin beta E) (AB323819)
Example of Mouse INBHE (Inhibin Beta E) standard curve
Reactivity data
{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "cELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
Product details
Mouse INBHE ELISA Kit (Inhibin beta E) (ab323819) is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of INHbE in mouse serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Precision
[ { "reproducibilityType": "Intra", "sample": "Sample", "replicates": 3, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 10" }, { "reproducibilityType": "Inter", "sample": "Sample", "replicates": 8, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 12" } ]
Recovery
[ { "sample": "Serum", "range": "78 - 94 %", "average": "= 88" }, { "sample": "EDTA Plasma", "range": "90 - 101 %", "average": "= 95" }, { "sample": "Heparin Plasma", "range": "87 - 104 %", "average": "= 97" } ]
What's included?
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Properties and storage information
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Please refer to protocols
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
- Download websiteProtocolBooklet|en
Target data
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.. Activin E is a homodimer of INHBE secreted by the liver that plays a crucial role in regulating metabolic homeostasis particularly in lipid metabolism and energy homeostasis. Plays a central role in the regulation of adipose tissue lipolysis by preventing the influx of fatty acids from adipose tissue into the liver (PubMed : 39948368). Mechanistically, signals via ACVR1C to activate SMAD2/3 signaling, suppressing PPARG target genes in adipose tissue, thereby reducing liver lipid content and improving glycemic control (PubMed : 37523551, PubMed : 39948368). Induces beige adipocyte formation and thermogenesis in response to cold exposure (Ref.5).
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