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AB285262

Mouse PreAlbumin ELISA Kit

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Mouse PreAlbumin ELISA Kit is a Sandwich ELISA for the measurement of Mouse PreAlbumin in Mouse in Biofluids, Cell/Tissue Extracts samples.

View Alternative Names

Transthyretin, Prealbumin, Ttr

1 Images
Sandwich ELISA - Mouse PreAlbumin ELISA Kit (AB285262)
  • sELISA

Supplier Data

Sandwich ELISA - Mouse PreAlbumin ELISA Kit (AB285262)

Mouse PreAlbumin ELISA Kit.

Typical Standard Curve : These standard curves are for demonstration only. A standard curve must be run with each assay.

Key facts

Detection method

Colorimetric

Sample types

Plasma, Tissue Homogenate, Serum, Other biological fluids

Reacts with

Mouse

Assay type

Sandwich

Results type

Quantitative

Sensitivity

< 4.68 ng/mL

Range

7.81 - 500 ng/mL

Assay Platform

Microplate (12 x 8 well strips)

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Secondary Antibodies

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Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

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Primary Antibodies

AB75815

Anti-Prealbumin antibody [EP2929Y]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prealbumin antibody [EP2929Y] (AB75815)

  • 5
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This Mouse PreAlbumin ELISA kit ab285262 (previously called Transthyretin (TTR) ELISA Kit, E4310) is a sandwich ELISA assay for the quantitative measurement of mouse PreAlbumin in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of mouse PreAlbumin captured from the samples.

This product is manufactured by BioVision, an Abcam company and was previously called E4310 Transthyretin (TTR) (Mouse) ELISA Kit. E4310-100 is the same size as the 96 test size of ab285262.

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Precision

[ { "reproducibilityType": "Intra", "sample": "Overall", "replicates": 0, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 8" }, { "reproducibilityType": "Inter", "sample": "Overall", "replicates": 0, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 10" } ]
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What's included?

{ "values": { "96Test": { "sellingSize": "96 Test", "publicAssetCode":"ab285262-96Test", "assetComponentDetails": [ { "size":"1 x 1 Unit", "name":"Micro ELISA Plate", "number":"AB285262-CMP05", "productcode":"" }, { "size":"5 x 1 Unit", "name":"Plate sealers", "number":"AB285262-CMP06", "productcode":"" }, { "size":"1 x 20 mL", "name":"Sample and Standard Dilution Buffer", "number":"AB285262-CMP07", "productcode":"" }, { "size":"1 x 10 mL", "name":"Antibody dilution buffer", "number":"AB285262-CMP01", "productcode":"" }, { "size":"1 x 10 mL", "name":"SABC dilution buffer", "number":"AB285262-CMP04", "productcode":"" }, { "size":"1 x 30 mL", "name":"25X Wash buffer", "number":"AB285262-CMP10", "productcode":"" }, { "size":"1 x 120 µL", "name":"Biotin/Detection antibody (Concentrated)", "number":"AB285262-CMP02", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Lyophilized Standard", "number":"AB285262-CMP03", "productcode":"" }, { "size":"1 x 10 mL", "name":"Stop Solution", "number":"AB285262-CMP11", "productcode":"" }, { "size":"1 x 120 µL", "name":"HRP-Streptavidin Conjugate (SABC)", "number":"AB285262-CMP08", "productcode":"" }, { "size":"1 x 10 mL", "name":"TMB Substrate", "number":"AB285262-CMP09", "productcode":"" } ] } } }
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
+4°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Prealbumin also known as transthyretin is a protein with a molecular mass of approximately 55 kDa. The liver primarily synthesizes prealbumin and it is present in the bloodstream. Functionally prealbumin transports thyroxine and retinol-binding protein-retinol complex facilitating the distribution of these molecules to target tissues. As such it plays an integral role in maintaining retinol and thyroid hormone homeostasis.
Biological function summary

Prealbumin interacts with retinol-binding protein to form a complex essential for vitamin A transportation. This complex prevents renal filtration of retinol-binding protein thereby conserving vitamin A in circulation. The protein's role extends beyond transport as it influences neurophysiological processes due to its ability to bind thyroid hormones and affect gene expression related to metabolism. Prealbumin is primarily a part of the thyroxine-transferring complex reinforcing its critical position in hormonal and vitamin dynamics.

Pathways

Prealbumin's role in the thyroxine-binding globulin pathway highlights its importance in the endocrine system. Another pathway where prealbumin contributes significantly is the vitamin A metabolic pathway. In these pathways prealbumin maintains functional relationships with proteins like retinol-binding protein and thyroxine-binding globulin which jointly modulate thyroid hormone transport and vitamin A dynamics across cellular membranes.

Prealbumin directly associates with familial amyloid polyneuropathy and malnutrition. Familial amyloid polyneuropathy involves the deposition of prealbumin-derived amyloid fibrils in peripheral nerves impacting neuron function. In malnutrition decreased prealbumin levels serve as a biomarker reflecting poor nutritional status. Clinically prealbumin's relation to retinol-binding protein and thyroid hormone levels facilitates its use in diagnosing and monitoring these conditions.
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Product protocols

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Target data

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
See full target information Ttr
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websiteProtocolBooklet
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Product promise

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