Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free
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(1 Publication)
Mouse Monoclonal 67kDa Laminin Receptor antibody. Carrier free. Suitable for ICC/IF, Flow Cyt, WB, Protein Array, IHC-P and reacts with Human, Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human RPSA.
View Alternative Names
LAMBR, LAMR1, RPSA, Small ribosomal subunit protein uS2, 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 40S ribosomal protein SA, 67 kDa laminin receptor, Colon carcinoma laminin-binding protein, Laminin receptor 1, Laminin-binding protein precursor p40, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, 37LRP, LRP/LR, 67LR, LamR, LBP/p40
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Formalin-fixed, paraffin-embedded human tonsil tissue stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml in immunohistochemical analysis.
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- Flow Cyt
Unknown
Flow Cytometry - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Flow Cytometric analysis of paraformaldehyde-fixed Raji (Human Burkitt's lymphoma cell line) cells labelling 67kDa Laminin Receptor using ab268079 at at 2 μg/ml followed by goat anti-Mouse IgG-CF488 (blue) and Isotype Control (Red).
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Formalin-fixed, paraffin-embedded human cervix carcinoma tissue stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml in immunohistochemical analysis.
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Formalin-fixed, paraffin-embedded human breast carcinoma tissue stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml in immunohistochemical analysis.
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Formalin-fixed, paraffin-embedded human basal cell carcinoma tissue stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml in immunohistochemical analysis.
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Immunofluorescent staining of HeLa (Human epithelial cell line from cervix adenocarcinoma) cells stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are labeled with RedDot (red).
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Immunofluorescent staining of paraformaldehyde-fixed Raji (Human Burkitt's lymphoma cell line) cells stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are labeled with RedDot (red).
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Formalin-fixed, paraffin-embedded human colon carcinoma tissue stained for 67kDa Laminin Receptor using ab268079 at 2 μg/ml in immunohistochemical analysis.
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
- WB
Unknown
Western blot - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079)
All lanes:
Western blot - Anti-67kDa Laminin Receptor antibody [RPSA/2699] (<a href='/en-us/products/primary-antibodies/67kda-laminin-receptor-antibody-rpsa-2699-ab268079'>ab268079</a>) at 2 µg/mL
Lane 1:
THP-1 (Human monocytic leukemia cell line) cell lysate
Lane 2:
U937 (Human histiocytic lymphoma cell line) cell lysate
Lane 3:
SK-BR-3 (Human mammary gland adenocarcinoma cell line) cell lysate
Lane 4:
A431 (Human epidermoid carcinoma cell line) cell lysate
Predicted band size: 33 kDa
false
- Protein Array
Unknown
Protein Array - Anti-67kDa Laminin Receptor antibody [RPSA/2699] - BSA and Azide free (AB268200)
Protein Array containing more than 19,000 full-length human proteins using ab268079.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and Sodium azide (ab268079).
Reactivity data
Product details
ab268200 is the carrier-free version of ab268079.
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This receptor engages in cellular interactions that are essential for maintaining the integrity and architecture of tissues. It often associates with other proteins to form complexes which further strengthen its functional capabilities. By anchoring laminin to the cell surface it regulates cell signaling pathways that influence cell motility invasion and survival. These interactions suggest that the 67kDa Laminin Receptor's function goes beyond simple adhesion impacting cellular responsiveness to external matrix cues.
Pathways
The receptor influences the MAPK and PI3K/Akt signaling pathways which are significant in cell survival and proliferation. Through such pathways it interacts with numerous proteins including integrins and fibronectin receptors facilitating orchestrated cell signaling. This connectivity highlights the receptor's role in cellular communication networks contributing to dynamic processes like wound healing and angiogenesis.
Product protocols
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Target data
Publications (1)
Recent publications for all applications. Explore the full list and refine your search
Journal for immunotherapy of cancer 11: PubMed37072348
2023
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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