Anti-AACT antibody [5G3C11] - C-terminal
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(1 Review)
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(1 Publication)
Mouse Monoclonal AACT antibody. C-terminal. Suitable for Flow Cyt, WB, IHC-P and reacts with Human, Transfected cell lysate - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human SERPINA3 aa 250 to C-terminus.
View Alternative Names
AACT, GIG24, GIG25, SERPINA3, Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AACT antibody [5G3C11] - C-terminal (AB201987)
Immunohistochemical analysis of paraffin-embedded Human endometrial cancer tissue labeling AACT with ab201987 at 1/200 dilution.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AACT antibody [5G3C11] - C-terminal (AB201987)
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissue labeling AACT with ab201987 at 1/200 dilution.
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-AACT antibody [5G3C11] - C-terminal (AB201987)
Flow cytometric analysis of A549 cells using ab201987 at 1/200 dilution (green) and negative control (red).
- WB
Supplier Data
Western blot - Anti-AACT antibody [5G3C11] - C-terminal (AB201987)
All lanes:
Western blot - Anti-AACT antibody [5G3C11] - C-terminal (ab201987) at 1/500 dilution
Lane 1:
HEK293 cell lysate
Lane 2:
AACT (AA: 279-432)-hIgGFc transfected HEK293 cell lysate
Predicted band size: 47 kDa
false
- WB
Supplier Data
Western blot - Anti-AACT antibody [5G3C11] - C-terminal (AB201987)
All lanes:
Western blot - Anti-AACT antibody [5G3C11] - C-terminal (ab201987) at 1/500 dilution
All lanes:
A549 cell lysate
Predicted band size: 47 kDa
false
- WB
Supplier Data
Western blot - Anti-AACT antibody [5G3C11] - C-terminal (AB201987)
All lanes:
Western blot - Anti-AACT antibody [5G3C11] - C-terminal (ab201987) at 1/500 dilution
All lanes:
AACT (AA: 279-432) recombinant protein
Predicted band size: 47 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Purification notes
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Alpha-1-antichymotrypsin plays a role in regulating protease activity to maintain tissue integrity. AACT forms part of a complex that involves other protease inhibitors and enzymes contributing to the balance of protein breakdown and regeneration. Its presence in the extracellular matrix highlights its structural and protective functions supporting cells against enzyme-mediated degradation.
Pathways
Alpha-1-antichymotrypsin takes part in inflammatory and immune response pathways. It interacts within the acute phase response pathway a system activated during inflammatory events. This protein's relationship with other protease inhibitors such as alpha-1-antitrypsin accentuates its role in controlling proteolytic enzymes that could otherwise propagate unchecked inflammation and tissue damage.
Product protocols
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Target data
Publications (1)
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Nature communications 12:6839 PubMed34824237
2021
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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