Rabbit Polyclonal AATK antibody. Suitable for WB, IHC-P and reacts with Mouse, Recombinant full length protein - Human, Rat, Pig, Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human AATK aa 1200 to C-terminus.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.12% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human AATK aa 1200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q6ZMQ8
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Expected | Tested |
| Mouse | Tested | Expected |
| Rat | Tested | Expected |
| Pig | Tested | Expected |
| Recombinant full length protein - Human | Tested | Not recommended |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 0.50000-2.00000 µg/mL | Notes - |
Species Recombinant full length protein - Human | Dilution info 0.50000-2.00000 µg/mL | Notes - |
Species Rat | Dilution info 0.50000-2.00000 µg/mL | Notes - |
Species Pig | Dilution info 0.50000-2.00000 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5.00000-20.00000 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Pig | Dilution info Use at an assay dependent concentration. | Notes - |
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Recombinant full length protein - Human | Dilution info - | Notes - |
Alternative names
AATYK, KIAA0641, LMR1, LMTK1, AATK, Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP
Rabbit Polyclonal AATK antibody. Suitable for WB, IHC-P and reacts with Mouse, Recombinant full length protein - Human, Rat, Pig, Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human AATK aa 1200 to C-terminus.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.12% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human AATK aa 1200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q6ZMQ8
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
ab231529 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
AATK also known as Apoptosis-Associated Tyrosine Kinase functions mechanically as a kinase that contains a domain for kinase activity. It has a molecular mass of approximately 165 kDa. Researchers have found AATK expression across various tissues notably in the nervous system. This wide expression suggests its involvement in critical cellular processes.
- Biological function summary
AATK influences the regulation of apoptosis and promotes neurite outgrowth. It does not appear to be part of a larger protein complex. In neurons AATK participates in processes that control cell death and differentiation which indicates its role in neuronal development and function.
- Pathways
AATK plays roles in the apoptosis signaling and neuronal differentiation pathways. These pathways integrate signals to guide cellular fate decisions. AATK interacts with proteins like p53 and other kinases that are well-known in regulating cell cycle and apoptotic processes.
- Associated diseases and disorders
AATK has associations with neurodegenerative diseases including Alzheimer's disease as well as some types of cancer. It shares connections with proteins such as tau in Alzheimer's where defective apoptosis and cell signaling contribute to pathological states. Further research into AATK may offer insights into therapeutic strategies for these conditions.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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7 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AATK antibody (ab231529)
Paraffin-embedded human pancreatic cancer tissue stained for AATK using ab231529 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AATK antibody (ab231529)
Paraffin-embedded human prostate gland tissue stained for AATK using ab231529 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AATK antibody (ab231529)
Paraffin-embedded human stomach cancer tissue stained for AATK using ab231529 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AATK antibody (ab231529)
Paraffin-embedded human liver tissue stained for AATK using ab231529 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AATK antibody (ab231529)
Paraffin-embedded human kidney tissue stained for AATK using ab231529 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Western blot - Anti-AATK antibody (ab231529)
All lanes: Western blot - Anti-AATK antibody (ab231529) at 3 µg/mL
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
Lane 3: Pig brain lysate
SecondaryAll lanes: HRP-linked guinea pig anti-rabbit at 1/2000 dilution
Predicted band size: 145 kDa
Western blot - Anti-AATK antibody (ab231529)
AATK Western blot staining of Recombinant human AATK protein using rabbit Anti-AATK antibody
All lanes: Western blot - Anti-AATK antibody (ab231529) at 3 µg/mL
All lanes: Recombinant human AATK protein
SecondaryAll lanes: HRP-linked guinea pig anti-rabbit at 1/2000 dilution
Predicted band size: 145 kDa
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