Rabbit Polyclonal ABLIM3 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ABLIM3 aa 400 to C-terminus.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human ABLIM3 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link O94929
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
| Mouse | Predicted |
| Rat | Predicted |
| Cow | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat, Cow, Mouse | Dilution info - | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.
Alternative names
KIAA0843, HMFN1661, ABLIM3, Actin-binding LIM protein 3, abLIM-3, Actin-binding LIM protein family member 3
Recommended products
Rabbit Polyclonal ABLIM3 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ABLIM3 aa 400 to C-terminus.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human ABLIM3 aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link O94929
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
ABLIM3 short for Actin Binding LIM protein 3 is a target with a mass of approximately 75 kDa. This protein contains several LIM domains and primarily binds with actin filaments. It functions as an adaptor facilitating cytoskeletal dynamics and signal transmissions. You find ABLIM3 expressed in various tissues including central nervous tissue and muscles which indicates its broad role in maintaining cellular framework and functions.
- Biological function summary
ABLIM3 plays a critical role in cell shape and motility by connecting actin filaments with signal transduction pathways. This protein associates with the cytoskeleton and influences changes in actin organization. It often works as part of a protein complex that includes LIM domain proteins which modulate actin cytoskeleton stability and cell signaling. These interactions highlight its importance in controlling cellular responses to extracellular signals.
- Pathways
ABLIM3 is integral to pathways related to cell motility and cytoskeletal organization. It contributes to the arrangement of actin filaments affecting cell migration and adhesion processes. In particular ABLIM3 interacts with proteins like integrins and vinculin in these pathways coordinating changes necessary for cellular movement and structure. These associations support cellular architecture and movement adaptations.
- Associated diseases and disorders
Abnormal expressions of ABLIM3 relate to certain cancers and neurological disorders. In cancer especially in metastatic diseases disruptions in ABLIM3-mediated signaling can lead to altered cell motility promoting tumor growth and spread. For neurological disorders ABLIM3 connections with proteins such as actin-related proteins may contribute to pathologies involving synaptic stability and neurodegeneration. These links illustrate the significant impact of ABLIM3 in health and disease contexts.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
Western blot - Anti-ABLIM3 antibody (ab153804)
7.5% SDS PAGE
All lanes: Western blot - Anti-ABLIM3 antibody (ab153804) at 1/500 dilution
All lanes: NT2D1 whole cell lysate at 30 µg
Predicted band size: 57 kDa, 66 kDa, 78 kDa
Downloads
Product protocols
- Visit the general protocols
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