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Mouse Polyclonal ABLIM3 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ABLIM3.


Images

Western blot - Anti-ABLIM3 antibody (AB67721), expandable thumbnail

Publications

Key facts

Isotype
IgG
Host species
Mouse
Storage buffer

pH: 7.4
Constituents: PBS

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Recombinant Full Length Protein corresponding to Human ABLIM3. Database link O94929

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested

Tested
Tested

Species
Human
Dilution info
1/500.00000 - 1/1000.00000
Notes

-

Associated Products

Select an associated product type

1 product for Alternative Product

Target data

Function

May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.

Alternative names

KIAA0843, HMFN1661, ABLIM3, Actin-binding LIM protein 3, abLIM-3, Actin-binding LIM protein family member 3

Recommended products

Mouse Polyclonal ABLIM3 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ABLIM3.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Recombinant Full Length Protein corresponding to Human ABLIM3. Database link O94929
Purification technique
Affinity purification Protein A
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

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Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

ABLIM3 short for Actin Binding LIM protein 3 is a target with a mass of approximately 75 kDa. This protein contains several LIM domains and primarily binds with actin filaments. It functions as an adaptor facilitating cytoskeletal dynamics and signal transmissions. You find ABLIM3 expressed in various tissues including central nervous tissue and muscles which indicates its broad role in maintaining cellular framework and functions.

Biological function summary

ABLIM3 plays a critical role in cell shape and motility by connecting actin filaments with signal transduction pathways. This protein associates with the cytoskeleton and influences changes in actin organization. It often works as part of a protein complex that includes LIM domain proteins which modulate actin cytoskeleton stability and cell signaling. These interactions highlight its importance in controlling cellular responses to extracellular signals.

Pathways

ABLIM3 is integral to pathways related to cell motility and cytoskeletal organization. It contributes to the arrangement of actin filaments affecting cell migration and adhesion processes. In particular ABLIM3 interacts with proteins like integrins and vinculin in these pathways coordinating changes necessary for cellular movement and structure. These associations support cellular architecture and movement adaptations.

Associated diseases and disorders

Abnormal expressions of ABLIM3 relate to certain cancers and neurological disorders. In cancer especially in metastatic diseases disruptions in ABLIM3-mediated signaling can lead to altered cell motility promoting tumor growth and spread. For neurological disorders ABLIM3 connections with proteins such as actin-related proteins may contribute to pathologies involving synaptic stability and neurodegeneration. These links illustrate the significant impact of ABLIM3 in health and disease contexts.

Product promise

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1 product image

  • Western blot - Anti-ABLIM3 antibody (ab67721), expandable thumbnail

    Western blot - Anti-ABLIM3 antibody (ab67721)

    All lanes: Western blot - Anti-ABLIM3 antibody (ab67721) at 1/500 dilution

    Lane 1: ABLIM3 transfected 293T cell lysate at 25 µg

    Lane 2: Non transfected 293T cell lysate at 25 µg

    Secondary

    All lanes: Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size: 78 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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