JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB108209

Anti-ACE2 antibody [EPR4436]

  • RabMAb
  • Recombinant
  • KO Validated
  • 20ul selling size
  • What is this?

4

(8 Reviews)

|

(38 Publications)

Rabbit Recombinant Monoclonal ACE2 antibody. Suitable for IHC-P, IP, WB and reacts with Human samples. Cited in 38 publications.

View Alternative Names

UNQ868/PRO1885, ACE2, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, Angiotensin-converting enzyme-related carboxypeptidase, Metalloprotease MPROT15, ACEH, ACE-related carboxypeptidase

7 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4436] (AB108209)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4436] (AB108209)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling ACE2 with ab108209 at 1/100. Heat mediated antigen retrieval was performed before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4436] (AB108209)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4436] (AB108209)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis tissue labelling ACE2 with ab108209 at 1/100. Heat mediated antigen retrieval was performed before commencing with IHC staining protocol.

Immunoprecipitation - Anti-ACE2 antibody [EPR4436] (AB108209)
  • IP

Lab

Immunoprecipitation - Anti-ACE2 antibody [EPR4436] (AB108209)

ab108209 Immunoprecipitating ACE2 in human testis tissue lysate. 0.35 mg of tissue lysate was incubated with 2 μg primary antibody (1/30). For western blotting a HRP-conjugated Veriblot for IP Detection Reagent (ab131366) (1/1000) was used to confirm successful immunoprecipitation.

Exposure time : 1 second.
Blocking buffer and concentration : 5% NFDM/TBST.
Diluting buffer and concentration : 5% NFDM /TBST.

All lanes:

Immunoprecipitation - Anti-ACE2 antibody [EPR4436] (ab108209) at 1/500 dilution

Lane 1:

Human testis tissue lysate at 10 µg

Lane 2:

ab108209 + Human testis tissue lysate

Lane 3:

Rabbit monoclonal IgG (<a href='/en-us/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a>) instead of ab108209 in Human testis tissue lysate

Predicted band size: 92 kDa

Observed band size: 110 kDa

false

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)
  • WB

Lab

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)

Lanes 1 - 4 : Merged signal (red and green). Green - ab108209 observed at 125 kDa. Red - loading control ab8245 (Mouse anti-GAPDH antibody [6C5]) observed at 37kDa.

ab108209 was shown to react with ACE2 in Caco-2 wild-type cells in western blot with loss of signal observed in ACE2 knockout cell line ab273731 (knockout cell lysate ab275516). Wild-type and ACE2 knockout Caco-2 cell lysates were subjected to SDS-PAGE. Membranes were blocked in fluorescent western blot (TBS-based) blocking solution before incubation with ab108209 and ab8245 (Mouse anti-GAPDH antibody [6C5]) overnight at 4°C at a 1 in 1000 Dilution and a 1 in 20000 dilution respectively. Blots were incubated with Goat anti-Rabbit IgG H&L (IRDye® 800CW) preabsorbed (ab216773) and Goat anti-Mouse IgG H&L (IRDye® 680RD) preabsorbed (ab216776) secondary antibodies at 1 in 20000 dilution for 1 hour at room temperature before imaging.

All lanes:

Western blot - Anti-ACE2 antibody [EPR4436] (ab108209) at 1/1000 dilution

Lane 1:

Wild-type Caco-2 cell lysate at 30 µg

Lane 2:

ACE2 knockout Caco-2 cell lysate at 30 µg

Lane 2:

Western blot - Human ACE2 knockout Caco-2 cell line (<a href='/en-us/products/cell-lines/human-ace2-knockout-caco-2-cell-line-ab273731'>ab273731</a>)

Lane 3:

Calu-3 cell lysate at 30 µg

Lane 4:

A549 cell lysate at 30 µg

Predicted band size: 92 kDa

Observed band size: 125 kDa

false

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)
  • WB

Lab

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)

Lanes 1 - 6 : Merged signal (red and green). Green - ab108209 observed at 120 kDa. Red - loading control, Mouse anti-Actin observed at 42kDa.

ab108209 was shown to react with ACE2 in western blot. Membranes were blocked in 3% milk in TBS-T (0.1% Tween®) before incubation with ab108209 and Mouse anti-Actin overnight at 4°C at a 1 in 1000 dilution and a 1 in 20000 dilution respectively. Blots were incubated with Goat anti-Rabbit IgG H&L (IRDye® 800CW) preabsorbed (ab216773) and Goat anti-Mouse IgG H&L (IRDye® 680RD) preabsorbed (ab216776) secondary antibodies at 1 in 20000 dilution for 1 hour at room temperature before imaging.

Absence of ACE2 expression in A549 cells aligns with previously reported mRNA and protein data (PMID 16282461; fig.2b and 2c).

All lanes:

Western blot - Anti-ACE2 antibody [EPR4436] (ab108209) at 1/1000 dilution

Lane 1:

Human testis cell lysate at 20 µg

Lane 2:

Human kidney cell lysate at 20 µg

Lane 3:

Human lung cell lysate at 20 µg

Lane 4:

HepG2 cell lysate at 20 µg

Lane 5:

Caco-2 cell lysate at 20 µg

Lane 6:

A549 cell lysate (negative control) at 20 µg

Predicted band size: 92 kDa

Observed band size: 120 kDa

false

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)
  • WB

Unknown

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)

All lanes:

Western blot - Anti-ACE2 antibody [EPR4436] (ab108209)

Lane 1:

Human fetal kidney lysate at 10 µg

Lane 2:

Human testis lysate at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 92 kDa

Observed band size: 115 kDa

false

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)
  • WB

Lab

Western blot - Anti-ACE2 antibody [EPR4436] (AB108209)

Lanes 1 - 4 : Merged signal (red and green). Green - ab108209 observed at 130 kDa. Red - loading control ab8245 (Mouse anti-GAPDH antibody [6C5]) observed at 37kDa.

ab108209 was shown to react with ACE2 in wild-type HepG2 cells in western blot with loss of signal observed in ACE2 knockout cell line ab273733 (knockout cell lysate ab275495). Wild-type and ACE2 knockout HepG2 cell lysates were subjected to SDS-PAGE. Membranes were blocked in 3% milk in TBS-T (0.1% Tween®) before incubation with ab108209 and ab8245 (Mouse anti-GAPDH antibody [6C5]) overnight at 4°C at a 1 in 1000 dilution and a 1 in 20000 dilution respectively. Blots were incubated with Goat anti-Rabbit IgG H&L (IRDye® 800CW) preabsorbed (ab216773) and Goat anti-Mouse IgG H&L (IRDye® 680RD) preabsorbed (ab216776) secondary antibodies at 1 in 20000 dilution for 1 hour at room temperature before imaging.

All lanes:

Western blot - Anti-ACE2 antibody [EPR4436] (ab108209) at 1/1000 dilution

Lane 1:

Wild-type HepG2 cell lysate at 30 µg

Lane 2:

ACE2 knockout HepG2 cell lysate at 30 µg

Lane 2:

Western blot - Human ACE2 knockout Hep G2 cell line (<a href='/en-us/products/cell-lines/human-ace2-knockout-hep-g2-cell-line-ab273733'>ab273733</a>)

Lane 3:

Calu-3 cell lysate at 30 µg

Lane 4:

A549 cell lysate at 30 µg

Predicted band size: 92 kDa

Observed band size: 130 kDa

false

  • Carrier free

    Anti-ACE2 antibody [EPR4436] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR4436

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, IP

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Alternative Products

Primary Antibodies

AB15348

Anti-ACE2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody (AB15348)

  • 5
  • 13
Primary Antibodies

AB89111

Anti-ACE2 antibody [MM0073-11A31]

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [MM0073-11A31] (AB89111)

  • 4
  • 4
Primary Antibodies

AB65863

Anti-ACE2 antibody

BOND RX™ Validated|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody (AB65863)

  • 5
  • 1
Primary Antibodies

AB108252

Anti-ACE2 antibody [EPR4435(2)]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4435(2)] (AB108252)

  • 4
  • 10
Cell Lines & Lysates

AB166833

Hep G2 whole cell lysate

  • 0
  • 0
Primary Antibodies

AB239924

Anti-ACE2 antibody [EPR4435(2)] - BSA and Azide free

BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACE2 antibody [EPR4435(2)] - BSA and Azide free (AB239924)

  • 4
  • 2

Complementary Products

Assay Kits

AB235649

Human ACE2 ELISA Kit

Recombinant|SimpleStep

ELISA - Human ACE2 ELISA Kit (AB235649)

  • 5
  • 1
Primary Antibodies

AB109131

Anti-TMPRSS2 antibody [EPR3862]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMPRSS2 antibody [EPR3862] (AB109131)

  • 5
  • 3
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB283943

Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [EPR24852-116] - BSA and Azide free

RabMAb|Recombinant

ELISA - Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [EPR24852-116] - BSA and Azide free (AB283943)

  • 0
  • 0
Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

  • 5
  • 88
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/250", "IHCP-species-notes": "<p>Heat up to 98°C, below boiling, and then let cool for 10-20 minutes. The use of an HRP/AP polymerized secondary antibody is recommended.</p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/10 - 1/100", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/100 - 1/250", "IHCP-species-notes": "<p>Heat up to 98°C, below boiling, and then let cool for 10-20 minutes. The use of an HRP/AP polymerized secondary antibody is recommended.</p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "1/10 - 1/100", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
style
left-column

Product details

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The ACE2 protein also known as angiotensin-converting enzyme 2 is an essential component in the renin-angiotensin system. It functions mechanically by converting the hormone angiotensin II to angiotensin-(1-7) which helps regulate blood pressure and fluid balance. The molecular weight of ACE2 is approximately 120 kDa. This protein is expressed in various tissues particularly the lungs heart kidneys and gastrointestinal tract. In cultured cells like Caco-2 cells researchers often study this expression.
Biological function summary

The ACE2 protein plays an important role in the regulation of cardiovascular and renal functions. It is a single-pass type I membrane protein and its activity reduces inflammation and oxidative stress in cells. ACE2 does not function as part of a larger protein complex but its enzymatic conversion has a substantial impact on reducing the effects of angiotensin II in the body leading to vasodilation and decreased blood pressure.

Pathways

ACE2 involvement is significant in the renin-angiotensin system and the kallikrein-kinin system. These pathways are essential for maintaining cardiovascular homeostasis. In the renin-angiotensin system ACE2 works in opposition to angiotensin-converting enzyme (ACE) balancing the effects through the production of angiotensin-(1-7) from angiotensin II. Additionally ACE2 interacts indirectly with proteins like angiotensin receptor type 1 (AT1) and angiotensin receptor type 2 (AT2) ensuring proper signaling and physiological responses.

ACE2 links closely with conditions such as hypertension and COVID-19. Increased activity of angiotensin II due to low ACE2 levels contributes to hypertension. In infectious disease SARS-CoV-2 virus responsible for COVID-19 uses ACE2 as an entry receptor to initiate infection in host cells. This interaction highlights the importance of ACE2 in disease pathogenesis and has prompted interest in ACE2 as a potential therapeutic target.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed : 27217402). Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II (PubMed : 10924499, PubMed : 10969042, PubMed : 11815627, PubMed : 14504186, PubMed : 19021774). Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin (PubMed : 10969042, PubMed : 11815627). Also cleaves other biological peptides, such as apelins (apelin-13, [Pyr1]apelin-13, apelin-17, apelin-36), casomorphins (beta-casomorphin-7, neocasomorphin) and dynorphin A with high efficiency (PubMed : 11815627, PubMed : 27217402, PubMed : 28293165). In addition, ACE2 C-terminus is homologous to collectrin and is responsible for the trafficking of the neutral amino acid transporter SL6A19 to the plasma membrane of gut epithelial cells via direct interaction, regulating its expression on the cell surface and its catalytic activity (PubMed : 18424768, PubMed : 19185582).. (Microbial infection) Acts as a receptor for human coronaviruses SARS-CoV and SARS-CoV-2, as well as human coronavirus NL63/HCoV-NL63.. Isoform 2. Non-functional as a carboxypeptidase.. Isoform 2. (Microbial infection) Non-functional as a receptor for human coronavirus SARS-CoV-2.
See full target information ACE2
style
left-column

Publications (38)

Recent publications for all applications. Explore the full list and refine your search

Molecular metabolism 101:102238 PubMed40907945

2025

Apolipoprotein E receptor 2 in endothelium promote glucose tolerance by mediating insulin delivery to skeletal muscle.

Applications

Unspecified application

Species

Unspecified reactive species

Anastasia Sacharidou,Ken L Chambliss,Jun Peng,Keiji Tanigaki,Md Nurul Islam,Shashank Sirsi,Andrew Lemoff,Kenneth Hoyt,Chieko Mineo,Philip W Shaul

Viruses 17: PubMed40872854

2025

The Tetraspanin CD9 Facilitates SARS-CoV-2 Infection and Brings Together Different Host Proteins Involved in SARS-CoV-2 Attachment and Entry into Host Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Vanessa Rivero,María Laura Saiz,Daniel Torralba,Carlos López-Larrea,Beatriz Suarez-Alvarez,Marta L DeDiego

Mammalian genome : official journal of the International Mammalian Genome Society 36:403-416 PubMed39985688

2025

New mouse model for inducible hACE2 expression enables to dissect SARS-CoV-2 pathology beyond the respiratory system.

Applications

Unspecified application

Species

Unspecified reactive species

Federica Gambini,Dominik Arbon,Petr Nickl,Vaclav Zatecka,Olha Fedosieieva,Juraj Labaj,Vendula Novosadova,Jana Trylcova,Jan Weber,Jan Prochazka,Jana Balounova,Radislav Sedlacek

Nature communications 16:766 PubMed39824810

2025

Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease.

Applications

Unspecified application

Species

Unspecified reactive species

Long Fung Chau,Simon Lillico,Tanja Opriessnig,Rosemary Blake,Luc Tardy,Chen-Hsuin Lee,Scott Maxwell,Claire Warren,Elizabeth Thornton,Catherine L Mclaughlin,Gerry McLachlan,Christine Tait-Burkard,Sarah Fletcher,Stephen Anderson,Sharon Brown,Louise Gibbard,Thomas Tzelos,Dawn MacMillan-Christensen,J Kenneth Baillie,David A Dorward,David J Griffiths,Finn Grey

Nature communications 15:1048 PubMed38316817

2024

Isolation and characterization of a pangolin-borne HKU4-related coronavirus that potentially infects human-DPP4-transgenic mice.

Applications

Unspecified application

Species

Unspecified reactive species

Luo-Yuan Xia,Zhen-Fei Wang,Xiao-Ming Cui,Yuan-Guo Li,Run-Ze Ye,Dai-Yun Zhu,Fang-Xu Li,Jie Zhang,Wen-Hao Wang,Ming-Zhu Zhang,Wan-Ying Gao,Lian-Feng Li,Teng-Cheng Que,Tie-Cheng Wang,Na Jia,Jia-Fu Jiang,Yu-Wei Gao,Wu-Chun Cao

International journal of molecular sciences 25: PubMed38256071

2024

The Abundant Distribution and Duplication of SARS-CoV-2 in the Cerebrum and Lungs Promote a High Mortality Rate in Transgenic hACE2-C57 Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Heng Li,Xin Zhao,Shasha Peng,Yingyan Li,Jing Li,Huiwen Zheng,Yifan Zhang,Yurong Zhao,Yuan Tian,Jinling Yang,Yibin Wang,Xinglong Zhang,Longding Liu

Nature 623:423-431 PubMed37914927

2023

Mouse genome rewriting and tailoring of three important disease loci.

Applications

Unspecified application

Species

Unspecified reactive species

Weimin Zhang,Ilona Golynker,Ran Brosh,Alvaro Fajardo,Yinan Zhu,Aleksandra M Wudzinska,Raquel Ordoñez,André M Ribeiro-Dos-Santos,Lucia Carrau,Payal Damani-Yokota,Stephen T Yeung,Camille Khairallah,Antonio Vela Gartner,Noor Chalhoub,Emily Huang,Hannah J Ashe,Kamal M Khanna,Matthew T Maurano,Sang Yong Kim,Benjamin R tenOever,Jef D Boeke

Frontiers in cardiovascular medicine 10:1266276 PubMed37823176

2023

Endothelial SARS-CoV-2 infection is not the underlying cause of COVID-19-associated vascular pathology in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Siqi Gao,Alan T Tang,Min Wang,David W Buchholz,Brian Imbiakha,Jisheng Yang,Xiaowen Chen,Peter Hewins,Patricia Mericko-Ishizuka,N Adrian Leu,Stephanie Sterling,Avery August,Kellie A Jurado,Edward E Morrisey,Hector Aguilar-Carreno,Mark L Kahn

Cell host & microbe 31:1154-1169.e10 PubMed37339625

2023

Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.

Applications

Unspecified application

Species

Unspecified reactive species

Nan Zhao,Jessica Sook Yuin Ho,Fanye Meng,Simin Zheng,Andrew P Kurland,Lu Tian,Martha Rea-Moreno,Xiangyang Song,Ji-Seon Seo,H Ümit Kaniskan,Aartjan J W Te Velthuis,Domenico Tortorella,Ya-Wen Chen,Jeffrey R Johnson,Jian Jin,Ivan Marazzi

Frontiers in microbiology 14:1175188 PubMed37350787

2023

A novel hACE2 knock-in mouse model recapitulates pulmonary and intestinal SARS-CoV-2 infection.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyang Zhou,Weiyang Sun,Yu Zhang,Hongjing Gu,Ruixuan Wang,Peng Xie,Yunkai Zhu,Minyue Qiu,Xiaoyan Ding,Hui Wang,Yuwei Gao,Jintao Li
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com