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AB36851

Anti-Adenovirus antibody

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(6 Publications)

Goat Polyclonal Adenovirus antibody. Suitable for ELISA, WB, ICC/IF and reacts with Adenovirus samples. Cited in 6 publications.

View Alternative Names

Adenovirus

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Adenovirus

Applications

ELISA, ICC/IF, WB

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Adenovirus": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Ion exchange chromatography
Purification notes
>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.
Storage buffer
Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Adenovirus also known by alternate names such as Adenoviren and Ad51 represents a group of medium-sized non-enveloped viruses with a double-stranded DNA genome. The adenovirus is approximately 90-100 nm in size and is notable for its icosahedral capsid structure. It primarily infects epithelial cells in the respiratory and gastrointestinal tracts but it can also affect other tissues. Its presence is recorded in diverse environments often acting as pathogens in humans and other animals.
Biological function summary

Adenoviruses function by hijacking the host cell's machinery to replicate their DNA and produce viral proteins. They do not form part of a larger complex; instead they independently orchestrate the synthesis of viral particles. Their proteins manipulate host cellular processes leading to cell lysis and viral release. Adenoviral proteins such as E1A and E1B play critical roles in their replication cycles and pathogenicity.

Pathways

Adenoviruses interact closely with pathways involved in cell cycle regulation and apoptosis. These viruses exploit cell cycle-associated proteins like p53 and Rb to immortalize host cells and evade apoptosis respectively. By bypassing normal regulatory checkpoints adenoviruses can ensure continuous replication and survival within the host.

Adenoviruses are commonly associated with conditions like acute respiratory diseases and gastroenteritis. They have a significant connection to the immune responses triggered in infected patients often involving proteins such as cytokines and chemokines. In some cases adenovirus-related infections can lead to severe outcomes in individuals with compromised immune systems demonstrating their impact on human health.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Adenovirus
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 5:106 PubMed35115660

2022

Carvedilol targets β-arrestins to rewire innate immunity and improve oncolytic adenoviral therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Joseph I Hoare,Bleona Osmani,Emily A O'Sullivan,Ashley Browne,Nicola Campbell,Stephen Metcalf,Francesco Nicolini,Jayeta Saxena,Sarah A Martin,Michelle Lockley

Cancers 12: PubMed32224979

2020

External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase.

Applications

Unspecified application

Species

Unspecified reactive species

Tzveta D Pokrovska,Egon J Jacobus,Rathi Puliyadi,Remko Prevo,Sally Frost,Arthur Dyer,Richard Baugh,Gonzalo Rodriguez-Berriguete,Kerry Fisher,Giovanna Granata,Katharine Herbert,William K Taverner,Brian R Champion,Geoff S Higgins,Len W Seymour,Janet Lei-Rossmann

Molecular therapy oncolytics 16:289-301 PubMed32195317

2020

NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Elaine Y L Leung,Darren P Ennis,Philippa R Kennedy,Christopher Hansell,Suzanne Dowson,Malcolm Farquharson,Pavlina Spiliopoulou,Jaya Nautiyal,Sophie McNamara,Leo M Carlin,Kerry Fisher,Daniel M Davis,Gerard Graham,Iain A McNeish

Antiviral research 153:78-84 PubMed29501624

2018

Bivalent vaccine platform based on ca influenza virus vaccine elicits protective immunity against human adenoviruses.

Applications

WB

Species

Unspecified reactive species

Hongjing Gu,Yaqian Gao,Shanshan Zhou,Fang Sun,Zhongpeng Zhao,Keyu Wang,Lingna Zhao,Peirui Zhang,Zhaohai Wang,Shaogeng Zhang,Xiliang Wang,Penghui Yang

Cell death & disease 8:3206 PubMed29238045

2017

RIPK3 promotes adenovirus type 5 activity.

Applications

IHC

Species

Unspecified reactive species

Melanie Weigert,Alex Binks,Suzanne Dowson,Elaine Y L Leung,Dimitris Athineos,Xinzi Yu,Margaret Mullin,Josephine B Walton,Clare Orange,Darren Ennis,Karen Blyth,Stephen W G Tait,Iain A McNeish

Molecular cancer research : MCR 14:44-55 PubMed26452665

2015

RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer.

Applications

WB

Species

Unspecified reactive species

Laura A Tookman,Ashley K Browne,Claire M Connell,Gemma Bridge,Carin K Ingemarsdotter,Suzanne Dowson,Atsushi Shibata,Michelle Lockley,Sarah A Martin,Iain A McNeish
View all publications
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