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AB152141

Anti-AFM antibody

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(1 Publication)

Rabbit Polyclonal AFM antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human AFM aa 350 to C-terminus.

View Alternative Names

ALB2, ALBA, AFM, Afamin, Alpha-albumin, Alpha-Alb

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human AFM aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P43652

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Alternative Products

Primary Antibodies

AB201034

Anti-AFM antibody [EPR19383]

RabMAb|Recombinant

Western blot - Anti-AFM antibody [EPR19383] (AB201034)

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Complementary Products

Assay Kits

AB323527

Human Afamin (AFM) ELISA Kit

SimpleStep

Sandwich ELISA - Human Afamin (AFM) ELISA Kit (AB323527)

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Proteins & Peptides

AB276516

Recombinant Human AFM protein (His tag)

SDS-PAGE - Recombinant Human AFM protein (His tag) (AB276516)

  • 0
  • 0
Primary Antibodies

AB219412

Anti-Wnt3a antibody [EPR21889]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Wnt3a antibody [EPR21889] (AB219412)

  • 0
  • 0
Primary Antibodies

AB92547

Anti-Vimentin antibody [EPR3776] - Cytoskeleton Marker

BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Multiplex immunohistochemistry - Anti-Vimentin antibody [EPR3776] - Cytoskeleton Marker (AB92547)

  • 5
  • 92
Primary Antibodies

AB82411

Anti-Transferrin antibody - Serum Loading Control

Lab Essentials

Western blot - Anti-Transferrin antibody - Serum Loading Control (AB82411)

  • 5
  • 8
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

AFM also known as Afamin is a glycoprotein assigned to the albumin family. Its molecular mass is approximately 87 kDa. This protein is mainly expressed in the liver and secreted into the bloodstream. It possesses binding affinity for vitamin E which suggests a role in transport and metabolic processes. It shares structural similarities with other proteins in the albumin family contributing to its functional versatility.
Biological function summary

AFM plays a central role in the transport of lipids and vitamins particularly vitamin E throughout the body. It acts independently and does not participate in large protein complexes. AFM shows interactions with other lipid-binding proteins modulating their activities and ensuring efficient distribution of essential nutrients. Such interactions highlight the importance of AFM in maintaining cellular homeostasis and protecting cells from oxidative damage.

Pathways

AFM actively participates in metabolic and vitamin transport pathways collaborating with proteins like albumin and transthyretin. It notably influences lipid metabolism and antioxidative pathways thereby contributing to overall cellular defense mechanisms. AFM's functionality intertwines with the activities of these proteins indicating its essential role in finely tuned biological processes especially those involving lipid and vitamin management.

AFM has associations with metabolic and neurodegenerative conditions. Altered levels of AFM can correlate with diseases like type 2 diabetes and Alzheimer's disease. It interacts with other relevant proteins such as apolipoproteins impacting disease progression and symptomatology. These connections suggest that AFM could potentially be a biomarker or therapeutic target for managing such disorders opening avenues for future research and treatment strategies.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed : 26902720). Binds vitamin E (PubMed : 12463752, PubMed : 15952736). May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient (PubMed : 15952736). May be involved in the transport of vitamin E across the blood-brain barrier (PubMed : 19046407).
See full target information AFM
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Biological research 58:59 PubMed40877912

2025

The unique contributions of Rab11 and Rab35 to the completion of cell division.

Applications

Unspecified application

Species

Unspecified reactive species

Paulius Gibieža,Emilija Ratkevičiūtė,Girstautė Dabkevičiūtė,Vilma Petrikaitė
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Product promise

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