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AB249051

Anti-AIBZIP antibody [EPR7382] - BSA and Azide free

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(1 Publication)

Rabbit Recombinant Monoclonal AIBZIP antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

AIBZIP, CREB4, JAL, CREB3L4, Cyclic AMP-responsive element-binding protein 3-like protein 4, cAMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, Cyclic AMP-responsive element-binding protein 4, Transcript induced in spermiogenesis protein 40, hJAL, AIbZIP, ATCE1, CREB-4, cAMP-responsive element-binding protein 4, Tisp40

1 Images
Western blot - Anti-AIBZIP antibody [EPR7382] - BSA and Azide free (AB249051)
  • WB

Unknown

Western blot - Anti-AIBZIP antibody [EPR7382] - BSA and Azide free (AB249051)

This data was developed using ab151736, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-AIBZIP antibody [EPR7382] (<a href='/en-us/products/primary-antibodies/aibzip-antibody-epr7382-ab151736'>ab151736</a>) at 1/1000 dilution

Lane 1:

Human prostate cancer lysate at 10 µg

Lane 2:

Human breast cancer lysate at 10 µg

Lane 3:

PC3 cell lysate at 10 µg

Lane 4:

LnCaP cell lysate at 10 µg

Lane 5:

MCF7 cell lysate at 10 µg

Lane 6:

T47D cell lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP at 1/2000 dilution

Predicted band size: 43 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR7382

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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Product details

ab249051 is the carrier-free version of ab151736.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

AIBZIP also known as Activating Immune Response Protein BZIP is a transcription factor involved in regulating gene expression. This protein with a molecular mass of approximately 45 kDa plays an important role in cellular functioning. Researchers have observed AIBZIP expression mainly in the immune cells including B and T lymphocytes. It regulates genes involved in immune responses by binding to DNA at specific sites assisting in the control of gene transcription.
Biological function summary

AIBZIP is a regulator of immune cell communication and response. AIBZIP forms a complex with other bZIP family proteins enabling it to influence a wide range of cellular processes. AIBZIP modulates expression of cytokines and other immunologically relevant genes. Proper function of AIBZIP ensures cells can effectively respond to pathogens and maintain immune homeostasis.

Pathways

AIBZIP acts in the NF-kB signaling pathway and JAK-STAT pathway both important for immune response and inflammation regulation. It interacts with proteins like RelA in the NF-kB pathway which modulates inflammatory responses and STAT3 in the JAK-STAT pathway that affects cellular growth and differentiation. Through these pathways AIBZIP influences many immune system functions and contributes to the regulation of immune cell activity.

AIBZIP impacts conditions like autoimmune disorders and certain cancers. Dysregulation of AIBZIP can lead to improper immune responses contributing to autoimmune diseases such as lupus. It also links to cancerous processes by affecting the immune system’s ability to fight tumor cells interacting with proteins like p53 that are important for cell cycle regulation. Understanding these interactions can help in developing targeted therapies for such diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity).
See full target information CREB3L4
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 60:2744-2760.e9 PubMed40460835

2025

ATG9A and ARFIP2 cooperate to control PI4P levels for lysosomal repair.

Applications

Unspecified application

Species

Unspecified reactive species

Stefano De Tito,Eugenia Almacellas,Daniel Dai Yu,Emily Millard,Wenxin Zhang,Cecilia de Heus,Christophe Queval,Javier H Hervás,Enrica Pellegrino,Ioanna Panagi,Ditte Fogde,Teresa L M Thurston,Judith Klumperman,Maximiliano Gutierrez,Sharon A Tooze
View all publications
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Product promise

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For full details, please see our Terms & Conditions

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