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AB192603

Anti-Albumin antibody [EPR12774]

  • RabMAb
  • Recombinant
  • Lab Essentials
  • 20ul selling size
  • What is this?

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(21 Publications)

Anti-Albumin antibody [EPR12774] (ab192603) is a rabbit monoclonal antibody detecting Albumin in Western Blot, IHC-P. Suitable for Cow, Human, Mouse, Rat.

- Biophysical QC for unrivalled batch-batch consistency
- Over 10 publications

View Alternative Names

GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, ALB, Albumin

16 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Albumin antibody [EPR12774] (AB192603)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Albumin antibody [EPR12774] (AB192603)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver labeling Serum albumin with ab192603 at 1/300 dilution. A prediluted HRP Polymer Rabbit IgG was used as the secondary antibody. Counterstained with Hematoxylin. Negative control also shown.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST Low expression : HCT116 (PMID : 24357805, PMID : 28300829, PMID : 19513549), 293T (PMID : 24357805). In Western blot, anti-GAPDH antibody (ab181602) loading control staining at 1/200000 dilution. Anti- Bovine Serum Albumin antibody (ab192603) loading control staining at 1/1000 dilution. Exposure time : 48 aeconds

All lanes:

Western blot - Anti-Cystatin SN/CST1 antibody [EPR25933-111] (<a href='/en-us/products/primary-antibodies/cystatin-sn-cst1-antibody-epr25933-111-ab307416'>ab307416</a>) at 1/1000 dilution

Lane 1:

MDA-MB-231 (human breast adenocarcinoma epithelial cell) cytoplasmic fraction at 20 µg

Lane 2:

SW480 (human colorectal adenocarcinoma epithelial cell), whole cell lysate at 20 µg

Lane 3:

HCT116 (human colorectal carcinoma epithelial cell) whole cell lysate at 20 µg

Lane 4:

293T (human embryonic kidney epithelial cell) whole cell lysate at 20 µg

Lane 5:

MDA-MB-231 culture supernatant at 10 µL

Lane 6:

SW480 culture supernatant at 10 µL

Lane 7:

HCT116 culture supernatant at 10 µL

Lane 8:

293T culture supernatant at 10 µL

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Observed band size: 16 kDa

false

Exposure time: 48s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST.

The expression profile/ molecular weight observed is consistent with what has been described in the literature (PMID : 32117064).

In Western blot, anti-GAPDH antibody (ab181602) loading control staining at 1/200000 dilution, anti-BSA antibody (ab192603) loading control staining at 1/10000 dilution.

Low expression : placenta (PMID : 32117064).

Samples are non-boiled as boiling may cause protein aggregation.

This blot was developed using a high sensitivity ECL substrate. The high-sensitivity ECL substrate used allows for the detection of proteins in the mid-femtogram range.

All lanes:

Western blot - Anti-MFSD2A/NLS1 antibody [EPR24503-101] (<a href='/en-us/products/primary-antibodies/mfsd2a-nls1-antibody-epr24503-101-ab307690'>ab307690</a>) at 1/1000 dilution

Lane 1:

Human serum lysate at 20 µg

Lane 2:

Human placenta tissue lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Predicted band size: 60 kDa

Observed band size: 50 kDa,100 kDa

true

Exposure time: 15s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST Protein Z is a glycoprotein of approximately 75 kDa and detected as a 65-kDa band after treated with Peptide : N-glycosidase F (PNGase F). In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-Protein Z antibody [EPR25824-16] (<a href='/en-us/products/primary-antibodies/protein-z-antibody-epr25824-16-ab314743'>ab314743</a>) at 1/1000 dilution

Lane 1:

Untreated human serum lysate at 20 µg

Lane 2:

Human serum tissue lysate treated with Peptide:N-glycosidase F (PNGase F) at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Observed band size: 75 kDa,65 kDa

false

Exposure time: 15s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST Low expression : pancreas. In Western blot, Anti-GAPDH antibody [EPR16891] - Loading Control (ab181602) staining at 1/200000 dilution. In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-Protein Z antibody [EPR25824-16] (<a href='/en-us/products/primary-antibodies/protein-z-antibody-epr25824-16-ab314743'>ab314743</a>) at 1/1000 dilution

Lane 1:

Human plasma lysate at 20 µg

Lane 2:

Human serum lysate at 20 µg

Lane 3:

Human pancreas tissue lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Observed band size: 75 kDa

false

Exposure time: 6s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST The expression profile/ molecular weight observed is consistent with what has been described in the literature (PMID : 31324782, 21527525, 22345489). In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-Thrombin antibody [EPR25304-12] (<a href='/en-us/products/primary-antibodies/thrombin-antibody-epr25304-12-ab314480'>ab314480</a>) at 1/1000 dilution

All lanes:

Human plasma lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Observed band size: 50 kDa,60 kDa

false

Exposure time: 15s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Low expression : kidney.

The identity of the bands between 50 kDa and 75 kDa are unknown.

In Western blot, Anti-GAPDH antibody [EPR16891] - Loading Control (ab181602) staining at 1/200000 dilution.

In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] - Loading Control (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-C1QA antibody [EPR28764-66] (<a href='/en-us/products/primary-antibodies/c1qa-antibody-epr28764-66-ab315905'>ab315905</a>) at 1/1000 dilution

Lane 1:

Rat plasma lysate at 80 µg

Lane 2:

Rat kidney tissue lysate at 80 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Observed band size: 26 kDa,36 kDa,69 kDa

false

Exposure time: 81s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

All lanes:

Western blot - Anti-Albumin antibody [EPR12774] (ab192603) at 1/1000 dilution

Lane 1:

Mouse kidney at 10 µg

Lane 2:

Mouse spleen at 10 µg

Lane 3:

Rat brain at 10 µg

Lane 4:

Rat kidney at 10 µg

Lane 5:

Rat spleen at 10 µg

Lane 6:

Raw264.7 cell lysate at 10 µg

Lane 7:

PC-12 cell lysate at 10 µg

Lane 8:

NIH-3T3 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 134 kDa,137 kDa,69 kDa

Observed band size: 69 kDa

false

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST In Western blot, anti-Bovine Serum Albumin antibody ((ab192603) loading control staining at 1/1000 dilution. Exposure time : 180 seconds

All lanes:

Western blot - Anti-Transferrin antibody [EPR28141-177] - Serum Loading Control (<a href='/en-us/products/primary-antibodies/transferrin-antibody-epr28141-177-serum-loading-control-ab313583'>ab313583</a>) at 1/1000 dilution

All lanes:

Mouse plasma lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Observed band size: 76 kDa

false

Exposure time: 180s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Low expression : liver, kidney.

In Western blot, Anti-GAPDH antibody [EPR16891] - Loading Control (ab181602) staining at 1/200000 dilution.

In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] - Loading Control (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-C1QA antibody [EPR28764-66] (<a href='/en-us/products/primary-antibodies/c1qa-antibody-epr28764-66-ab315905'>ab315905</a>) at 1/1000 dilution

Lane 1:

Mouse plasma lysate at 20 µg

Lane 2:

Mouse liver tissue lysate at 20 µg

Lane 3:

Mouse serum lysate at 20 µg

Lane 4:

Mouse kidney tissue lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Observed band size: 26 kDa,36 kDa,69 kDa

false

Exposure time: 180s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST In Western blot, Anti-GAPDH antibody [EPR16891] - Loading Control ( ab181602) staining at 1/200000 dilution. In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] (ab192603) staining at 1/1000 dilution. Exposure time : 3 seconds

All lanes:

Western blot - Anti-Gentamicin antibody [EPR27991-65] (<a href='/en-us/products/primary-antibodies/gentamicin-antibody-epr27991-65-ab314126'>ab314126</a>) at 1/1000 dilution

Lane 1:

Untreated RAW264.7 (mouse Abelson murine leukemia virus-induced tumor macrophage) whole cell lysate at 20 µg

Lane 2:

RAW264.7 treated with 0.5mg/mL Gentamicin-crosslink-BSA for 4 hours whole cell lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

false

Exposure time: 3s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST.

This antibody cross-reacts with recombinant Prostaglandin E1, but not cross-react with recombinant Prostaglandin F1α or Prostaglandin F2α by western blot.

In Western blot, Anti-Albumin antibody [EPR12774] (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-Prostaglandin E2/1 antibody [EPR25228-27] (<a href='/en-us/products/primary-antibodies/prostaglandin-e2-1-antibody-epr25228-27-ab323269'>ab323269</a>) at 1/1000 dilution

Lane 1:

Prostaglandin E2 cross-linked to BSA at 10 ng

Lane 2:

Prostaglandin E1 cross-linked to BSA at 10 ng

Lane 3:

Prostaglandin F1α cross-linked to BSA at 10 ng

Lane 4:

Prostaglandin F2α cross-linked to BSA at 10 ng

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Observed band size: 67 kDa,69 kDa

false

Exposure time: 15s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

All lanes:

Western blot - Anti-Albumin antibody [EPR12774] (ab192603) at 1/1000 dilution

All lanes:

Bovine Serum albumin at 0.001 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated

Predicted band size: 69 kDa

Observed band size: 69 kDa

false

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

All lanes:

Western blot - Anti-Albumin antibody [EPR12774] (ab192603) at 1/10000 dilution

Lane 1:

HepG2 cell lysate at 20 µg

Lane 2:

Human plasma at 20 µg

Lane 3:

Human serum at 20 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 69 kDa

Observed band size: 69 kDa

false

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Supplier Data

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST.

In lane 1, anti-BSA could not detect the total level of cross-linked BSA due to the blocking of epitopes by serotonin.

In Western blot, Anti-Bovine Serum Albumin antibody [EPR12774] (ab192603) staining at 1/1000 dilution.

All lanes:

Western blot - Anti-Serotonin antibody [EPR24431-201] (<a href='/en-us/products/primary-antibodies/serotonin-antibody-epr24431-201-ab315150'>ab315150</a>) at 1/1000 dilution

Lane 1:

Serotonin cross-linked to BSA at 20 ng

Lane 2:

BSA

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Observed band size: 69 kDa

false

Exposure time: 70s

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)
  • WB

Lab

Western blot - Anti-Albumin antibody [EPR12774] (AB192603)

Blocking and diluting buffer and concentration : 5% NFDM/TBST.

This antibody does not cross-react with Oxidized Glutathione(GSSG) by western blot.

In Western blot, Anti-Albumin antibody [EPR12774] - Loading Control (ab192603) (1 : 1000) (67KDa).

All lanes:

Western blot - Anti-Reduced Glutathione(GSH) antibody [EPR26828-37] (<a href='/en-us/products/primary-antibodies/reduced-glutathionegsh-antibody-epr26828-37-ab326336'>ab326336</a>) at 1/1000 dilution

Lane 1:

Reduced Glutathione(GSH) cross-linked to BSA at 10 ng

Lane 2:

Oxidized Glutathione(GSSG) cross-linked to BSA at 10 ng

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Observed band size: 75 kDa,67 kDa

false

Exposure time: 59s

  • Carrier free

    Anti-Albumin antibody [EPR12774] - BSA and Azide free

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Albumin antibody [EPR12774]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Albumin antibody [EPR12774]

  • HRP

    HRP Anti-Albumin antibody [EPR12774]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR12774

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Cow, Human

Applications

IHC-P, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/300", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

Product details

What is this antibody validated in?
Anti-Albumin antibody [EPR12774] (ab192603) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Cow, Human, Mouse, Rat samples.

What is the molecular weight of Albumin?
Anti-Albumin [EPR12774] (ab192603) specifically detects a band for Albumin (UniProt: P02769) at a molecular weight of 69kDa.

Trusted by the scientific community
Anti-Albumin [EPR12774] (ab192603) was first used in a scientific publication in 2014 and has been cited over 10 times in peer-reviewed journals.

Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies.

Other related products
We have a range of other formats of antibody clone [EPR12774] also available for your convenience: ab192603, Carrier free - ab240330, Alexa Fluor® 488 - ab302577

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Conditional Ambient
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Albumin also known as ALB is a major plasma protein with a molecular mass of approximately 66.5 kDa. It predominantly gets synthesized in the liver and found abundantly in blood plasma. Albumin serves multiple functions including maintaining osmotic pressure and acting as a carrier protein for various endogenous substances like hormones fatty acids and bilirubin.
Biological function summary

Albumin plays a critical role in transporting small molecules like metabolites and drugs through the circulatory system. It is not a part of any complex but functions independently to bind transport and release various ligands. Albumin's affinity for hydrophobic molecules makes it essential for they to be solubilized in blood for proper metabolism and excretion.

Pathways

More than five binding sites on albumin facilitate its role in the fatty acid metabolism and renin-angiotensin system pathways. In fatty acid metabolism albumin interacts with transport proteins carrying fatty acids to tissues for energy production. Additionally during the renin-angiotensin system albumin modulates blood pressure through its interaction with angiotensin II which can influence vasoconstriction.

Researchers link albumin with nephrotic syndrome and liver cirrhosis. In nephrotic syndrome low levels of albumin (albumin low) can cause edema due to imbalanced osmotic pressure. In liver cirrhosis a reduction in albumin synthesis signifies liver damage. Albumin's interaction with proteins like angiotensin II correlates with complications such as hypertension further establishing the protein's role in health and disease contexts.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed : 19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed : 6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed : 6234017).
See full target information ALB

Publications (21)

Recent publications for all applications. Explore the full list and refine your search

Journal of extracellular biology 4:e70084 PubMed40901048

2025

MicroRNA (miRNA) in Plasma Small Extracellular Vesicles (sEV) as Potential Early Indicators of Dairy Cow Subfertility.

Applications

Unspecified application

Species

Unspecified reactive species

Pevindu Abeysinghe,Natalie Turner,Holly Flay,Susanne Meier,Leila Cuttle,Murray D Mitchell

Clinical and translational medicine 15:e70198 PubMed39834100

2025

Single-cell landscape of the intrahepatic ecosystem in alcohol-related liver disease.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaofang Zhao,Senyan Wang,Qi Liu,Wenjuan Wei,Xiaoyan Sun,Hao Song,Jing Xu,Shuijun Zhang,Hongyang Wang,Jing Fu

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 29:215-225 PubMed39806787

2025

Microglial galectin-3 increases with aging in the mouse hippocampus.

Applications

Unspecified application

Species

Unspecified reactive species

Hyun Joo Shin,So Jeong Lee,Hyeong Seok An,Ha Nyeoung Choi,Eun Ae Jeong,Jaewoong Lee,Kyung Eun Kim,Bong-Hoi Choi,Seung Pil Yun,Dawon Kang,Sang Soo Kang,Gu Seob Roh

Extracellular vesicles and circulating nucleic acids 5:119-137 PubMed39698410

2024

A comparative analysis of small extracellular vesicle (sEV) micro-RNA (miRNA) isolation and sequencing procedures in blood plasma samples.

Applications

Unspecified application

Species

Unspecified reactive species

Pevindu Abeysinghe,Natalie Turner,Murray D Mitchell

Advanced materials (Deerfield Beach, Fla.) 36:e2407156 PubMed39543808

2024

Biocooperative Regenerative Materials by Harnessing Blood-Clotting and Peptide Self-Assembly.

Applications

Unspecified application

Species

Unspecified reactive species

Soraya Padilla-Lopategui,Cosimo Ligorio,Wenhuan Bu,Chengcheng Yin,Domenico Laurenza,Carlos Redondo,Robert Owen,Hongchen Sun,Felicity R A J Rose,Thomas Iskratsch,Alvaro Mata

Scientific reports 13:5425 PubMed37012302

2023

Dynamics of inflammatory cytokine expression in bovine endometrial cells exposed to cow blood plasma small extracellular vesicles (sEV) may reflect high fertility.

Applications

Unspecified application

Species

Unspecified reactive species

Pevindu Abeysinghe,Natalie Turner,Eman Mosaad,Jayden Logan,Murray D Mitchell

Disease models & mechanisms 16: PubMed36728410

2023

A hepatoprotective role of peritumoral non-parenchymal cells in early liver tumorigenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Cheng Tian,Liyuan Li,Li Fan,Anthony Brown,Eric J Norris,Michelle Morrison,Evan S Glazer,Liqin Zhu

Archives of toxicology 96:3349-3361 PubMed36227364

2022

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.

Applications

Unspecified application

Species

Unspecified reactive species

Reham Hassan,Daniela González,Zaynab Hobloss,Lisa Brackhagen,Maiju Myllys,Adrian Friebel,Abdel-Latif Seddek,Rosemarie Marchan,Benedikt Cramer,Hans-Ulrich Humpf,Stefan Hoehme,Gisela H Degen,Jan G Hengstler,Ahmed Ghallab

Chemical research in toxicology 35:1533-1540 PubMed36074022

2022

Nonylphenol Promoted Epithelial-Mesenchymal Transition in Colorectal Cancer Cells by Upregulating the Expression of Regulator of Cell Cycle.

Applications

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Nian-Jie Zhang,Yuanwei Zhang,Shuo Yin,Du-Ji Ruan,Nian He,Xu Chen,Xue-Feng Yang

Archives of toxicology 96:2967-2981 PubMed35962801

2022

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.

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Reham Hassan,Adrian Friebel,Lisa Brackhagen,Zaynab Hobloss,Maiju Myllys,Daniela González,Wiebke Albrecht,Elsayed S I Mohammed,Abdel-Latif Seddek,Rosemarie Marchan,Cristina Cadenas,Benedikt Cramer,Hans-Ulrich Humpf,Lukas Hartl,Benedikt Simbrunner,Thomas Reiberger,Michael Trauner,Stefan Hoehme,Gisela H Degen,Jan G Hengstler,Ahmed Ghallab
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