Anti-ALDH2 antibody
5
(2 Reviews)
|
(2 Publications)
Rabbit Polyclonal ALDH2 antibody. Suitable for IHC-P, WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human ALDH2 conjugated to Keyhole Limpet Haemocyanin.
View Alternative Names
ALDM, ALDH2, ALDH class 2, ALDH-E2, ALDHI
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALDH2 antibody (AB115198)
ab115198 at 10 µg/ml staining ALDH2 Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
- Flow Cyt (Intra)
Unknown
Flow Cytometry (Intracellular) - Anti-ALDH2 antibody (AB115198)
Intracellular flow cytometric analysis of HepG2 cells, staining ALDH2 with ab115198 (bottom histogram), compared to a negative control cell (top histogram). A FITC-conjugated goat-anti-rabbit IgG was used as the secondary antibody.
- WB
Unknown
Western blot - Anti-ALDH2 antibody (AB115198)
All lanes:
Western blot - Anti-ALDH2 antibody (ab115198) at 1/50 dilution
Lane 1:
293 cell lysate, non-transfected at 2 µg
Lane 2:
293 cell lysate, transiently transfected with ALDH2 gene at 2 µg
Predicted band size: 56 kDa
Observed band size: 56 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ALDH2 serves a detoxifying function by preventing oxidative stress and promoting cellular health. As part of the larger aldehyde dehydrogenase family this enzyme forms homotetramer complexes to efficiently catalyze the oxidation of aldehydes. ALDH2 supplementation may enhance its activity in individuals with reduced function due to genetic polymorphisms providing potential therapeutic benefits.
Pathways
ALDH2 integrates into the alcohol metabolism and retinoic acid signaling pathways. In alcohol metabolism it collaborates with alcohol dehydrogenase enzymes such as ADH1 and ADH2 to process alcohol consumption compounds. In retinoic acid signaling ALDH2 helps regulate the biosynthesis of retinoic acid influencing cell proliferation and differentiation processes.
Product protocols
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Target data
Publications (2)
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Nature communications 13:7139 PubMed36414669
2022
Applications
Unspecified application
Species
Unspecified reactive species
ASN neuro 12:1759091420925977 PubMed32466659
2020
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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