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Rabbit Monoclonal MICB antibody - conjugated to Alexa Fluor® 488.

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Images

Flow Cytometry - Alexa Fluor® 488 Rabbit monoclonal [EPR26362-65] to MICB (AB323890), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Conjugation
Alexa Fluor® 488
Excitation/Emission
Ex: 495nm, Em: 519nm
Storage buffer

pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA

Form
Liquid
Clonality
Monoclonal

Immunogen

  • The exact immunogen used to generate this antibody is proprietary information.

Target data

Function

Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed:11491531, PubMed:11777960). Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production.

Alternative names

PERB11.2, MICB, MHC class I polypeptide-related sequence B, MIC-B

Rabbit Monoclonal MICB antibody - conjugated to Alexa Fluor® 488.

Key facts

Isotype
IgG
Conjugation
Alexa Fluor® 488
Excitation/Emission
Ex: 495nm, Em: 519nm
Form
Liquid
Clonality
Monoclonal
Immunogen
  • The exact immunogen used to generate this antibody is proprietary information.
Clone number
EPR26362-65
Purification technique
Affinity purification Protein A
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle, Store in the dark

Product promise

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1 product image

  • Flow Cytometry - Alexa Fluor® 488 Rabbit monoclonal [EPR26362-65] to MICB (ab323890), expandable thumbnail

    Flow Cytometry - Alexa Fluor® 488 Rabbit monoclonal [EPR26362-65] to MICB (ab323890)

    Flow Cytometry staining using rabbit Anti- antibody

    Flow cytometric analysis of 293T (human embryonic kidney epithelial cell, Left) / Daudi (human Burkitt's lymphoma lymphoblast, Middle) / K562 (human chronic myelogenous leukemia lymphoblast, Right) cells labelling MICB with ab323890 at 1/50 dilution (1ug) (Red) compared with a Rabbit IgG monoclonal [EPR25A] - Isotype Control (Alexa Fluor® 488) (Alexa Fluor® 488 Rabbit IgG, monoclonal [EPR25A] - Isotype Control ab199091) (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody).

    Gated on viable cells.

    Negative control: 293T, Daudi (PMID: 28154561).

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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