Alexa Fluor® 488 Anti-Thioredoxin 2 antibody [EPR15225]
- RabMAb
- Recombinant
- What is this?
Be the first to review this product! Submit a review
|
(0 Publication)
Rabbit Recombinant Monoclonal Thioredoxin 2 antibody - conjugated to Alexa Fluor® 488.
View Alternative Names
TRX2, TXN2, MTRX, Mt-Trx, Thioredoxin-2
Related conjugates and formulations (10)
-
Anti-Thioredoxin 2 antibody [EPR15225]
-
578 PE
PE Anti-Thioredoxin 2 antibody [EPR15225]
-
660 APC
APC Anti-Thioredoxin 2 antibody [EPR15225]
-
HRP Anti-Thioredoxin 2 antibody [EPR15225]
-
603 Alexa Fluor® 568
Alexa Fluor® 568 Anti-Thioredoxin 2 antibody [EPR15225]
-
565 Alexa Fluor® 555
Alexa Fluor® 555 Anti-Thioredoxin 2 antibody [EPR15225]
-
775 Alexa Fluor® 750
Alexa Fluor® 750 Anti-Thioredoxin 2 antibody [EPR15225]
-
Anti-Thioredoxin 2 antibody [EPR15225] - BSA and Azide free
-
617 Alexa Fluor® 594
Alexa Fluor® 594 Anti-Thioredoxin 2 antibody [EPR15225]
-
665 Alexa Fluor® 647
Alexa Fluor® 647 Anti-Thioredoxin 2 antibody [EPR15225]
Product details
How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Thioredoxin 2 participates in regulating mitochondrial redox homeostasis ensuring the protection of mitochondrial DNA against oxidative damage. It acts as a part of the mitochondrial thioredoxin system which includes thioredoxin reductase and NADPH as components. This system is important for the control of mitochondrial reactive oxygen species (ROS) and supports mitochondrial function by facilitating the synthesis of deoxyribonucleotides. The protein therefore plays an important role in cellular antioxidant defenses and in modulating mitochondrial apoptotic pathways.
Pathways
The involvement of Thioredoxin 2 is pivotal in several cellular signaling cascades including the antioxidant defense and apoptosis pathways. Within the redox signaling pathways TXN2 works in conjunction with cytochrome c and caspases to regulate apoptosis and prevent uncontrolled cell death. In pathways related to cellular oxidative stress Thioredoxin 2 interacts closely with glutathione to mediate cellular responses to oxidative damage maintaining balance between the production and removal of ROS.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Complementary Products
Primary Antibodies
AB321131
Alexa Fluor® 750 Anti-Matrin 3 antibody [EPR10635(B)]
Recombinant|RabMAb
- 0
- 0
![Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 647 Anti-EB3 antibody [EPR11421(B)] (AB203265)](https://content.abcam.com/products/images/alexa-fluor-647-eb3-antibody-epr11421b-ab203265--immunocytochemistry-immunofluorescence-img95667.jpg)
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com