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AB313075

Alexa Fluor® 568 Anti-Steroidogenic Factor 1 / SF-1 antibody [EPR19744]

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Rabbit Recombinant Monoclonal Steroidogenic Factor 1/SF-1 antibody - conjugated to Alexa Fluor® 568.

View Alternative Names

AD4BP, FTZF1, SF1, NR5A1, Steroidogenic factor 1, SF-1, STF-1, hSF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Steroidogenic Factor 1 / SF-1 antibody [EPR19744]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Steroidogenic Factor 1 / SF-1 antibody [EPR19744]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Steroidogenic Factor 1 / SF-1 antibody [EPR19744]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Steroidogenic Factor 1 / SF-1 antibody [EPR19744]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Steroidogenic Factor 1/SF-1 antibody [EPR19744]

  • Unconjugated

    Anti-Steroidogenic Factor 1/SF-1 antibody [EPR19744]

  • Carrier free

    Anti-Steroidogenic Factor 1/SF-1 antibody [EPR19744] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR19744

Isotype

IgG

Conjugation

Alexa Fluor® 568

Excitation/Emission

Ex: 578nm, Em: 603nm

Carrier free

No

Applications

Target Binding Affinity, Antibody Labelling

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues (PubMed : 27378692). Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1 (PubMed : 27378692). The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidylcholine (By similarity). Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
See full target information NR5A1
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Complementary Products

Proteins & Peptides

AB114599

Recombinant Human Steroidogenic Factor 1/SF-1 protein

SDS-PAGE - Recombinant Human Steroidogenic Factor 1/SF-1 protein (AB114599)

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Product promise

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For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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