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AB310757

Alexa Fluor® 594 Anti-Fibronectin antibody [EPR23110-25]

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Rabbit Recombinant Monoclonal Fibronectin antibody - conjugated to Alexa Fluor® 594.

View Alternative Names

FN, FN1, Fibronectin, Cold-insoluble globulin, CIG

  • 578 PE

    PE Anti-Fibronectin antibody [EPR23110-25]

  • 660 APC

    APC Anti-Fibronectin antibody [EPR23110-25]

  • HRP

    HRP Anti-Fibronectin antibody [EPR23110-25]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Fibronectin antibody [EPR23110-25]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Fibronectin antibody [EPR23110-25]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Fibronectin antibody [EPR23110-25]

  • 603 Alexa Fluor® 568

    Alexa Fluor® 568 Anti-Fibronectin antibody [EPR23110-25]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Fibronectin antibody [EPR23110-25]

  • Unconjugated

    Anti-Fibronectin antibody [EPR23110-25]

  • Carrier free

    Anti-Fibronectin antibody [EPR23110-25] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR23110-25

Isotype

IgG

Conjugation

Alexa Fluor® 594

Excitation/Emission

Ex: 590nm, Em: 617nm

Carrier free

No

Applications

Target Binding Affinity, Antibody Labelling

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed : 3024962, PubMed : 3593230, PubMed : 3900070, PubMed : 7989369). Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (PubMed : 3024962, PubMed : 3593230, PubMed : 3900070, PubMed : 7989369). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation (PubMed : 34089617).. Anastellin. Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.. Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5 : ITGB1 integrin receptor signaling.
See full target information FN1

Product promise

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