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AB310765

Alexa Fluor® 594 Anti-Sialoadhesin antibody [SP213] - C-terminal

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Rabbit Recombinant Monoclonal Sialoadhesin/CD169 antibody - conjugated to Alexa Fluor® 594.

View Alternative Names

CD169, SN, SIGLEC1, Sialoadhesin, Sialic acid-binding Ig-like lectin 1, Siglec-1

  • Unconjugated

    Anti-Sialoadhesin/CD169 antibody [SP213] - C-terminal

  • 578 PE

    PE Anti-Sialoadhesin antibody [SP213] (C-terminal)

  • 660 APC

    APC Anti-Sialoadhesin antibody [SP213] (C-terminal)

  • HRP

    HRP Anti-Sialoadhesin antibody [SP213] (C-terminal)

  • 603 Alexa Fluor® 568

    Alexa Fluor® 568 Anti-Sialoadhesin/CD169 antibody [SP213] - C-terminal

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Sialoadhesin antibody [SP213] - C-terminal

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Sialoadhesin/CD169 antibody [SP213] - C-terminal

  • Carrier free

    Anti-Sialoadhesin/CD169 antibody [SP213] - BSA and Azide free

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Sialoadhesin antibody [SP213] - C-terminal

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Sialoadhesin antibody [SP213] - C-terminal

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

SP213

Isotype

IgG

Conjugation

Alexa Fluor® 594

Excitation/Emission

Ex: 590nm, Em: 617nm

Carrier free

No

Applications

Antibody Labelling, Target Binding Affinity

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response (PubMed : 12940982, PubMed : 33489013). Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs) (PubMed : 28129379). In turn, enhances macrophage-to-T-cell transmission of several viruses including HIV-1 or SARS-CoV-2 (PubMed : 28129379, PubMed : 34782760). Acts as an endocytic receptor mediating clathrin dependent endocytosis. Preferentially binds to alpha-2,3-linked sialic acid (PubMed : 12940982). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. Plays a role in the inhibition of antiviral innate immune by promoting TBK1 degradation via TYROBP and TRIM27-mediated ubiquitination (PubMed : 26358190).. (Microbial infection) Facilitates viral cytoplasmic entry into activated dendritic cells via recognition of sialylated gangliosides pesent on viral membrane.
See full target information SIGLEC1
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Product promise

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