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Rabbit Monoclonal SOX10 antibody - conjugated to Alexa Fluor® 594. Suitable for ICC/IF, Flow Cyt and reacts with Human, Mouse samples.

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Images

Flow Cytometry - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (AB311668), expandable thumbnail
  • Flow Cytometry - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (AB311668), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (AB311668), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (AB311668), expandable thumbnail

Key facts

Isotype

IgG

Host species

Rabbit

Conjugation

Alexa Fluor® 594

Excitation/Emission

Ex: 590nm, Em: 617nm

Storage buffer

pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA

Form

Liquid

Clonality

Monoclonal

Immunogen

  • The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
ICC/IFFlow Cyt
Human
Tested
Tested
Mouse
Tested
Tested

Tested
Tested

Species

Human

Dilution info

1/50

Notes

-

Species

Mouse

Dilution info

1/50

Notes

-

Tested
Tested

Species

Human

Dilution info

1/500

Notes

-

Species

Mouse

Dilution info

1/500

Notes

-

Associated Products

Select an associated product type

1 product for Alternative Version

Target data

Function

Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity).

Alternative names

Transcription factor SOX-10, SOX10

Recommended products

Rabbit Monoclonal SOX10 antibody - conjugated to Alexa Fluor® 594. Suitable for ICC/IF, Flow Cyt and reacts with Human, Mouse samples.

Key facts

Isotype

IgG

Conjugation

Alexa Fluor® 594

Excitation/Emission

Ex: 590nm, Em: 617nm

Form

Liquid

Clonality

Monoclonal

Immunogen
  • The exact immunogen used to generate this antibody is proprietary information.
Clone number

SP267

Purification technique

Affinity purification Protein A

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle, Store in the dark

Notes

This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

4 product images

  • Flow Cytometry - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668), expandable thumbnail

    Flow Cytometry - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668)

    Flow Cytometry analysis of B16-F0 (mouse skin melanoma cell) labeling SOX10 with ab311668 at 1/500 dilution (0.1 μg)/Red. Cells were fixed with 4% Paraformaldehyde and permeabilised with 90% methanol. A Rabbit IgG monoclonal [EPR25A] - Isotype Control (Alexa Fluor® 594) (Alexa Fluor® 594 Rabbit IgG, monoclonal [EPR25A] - Isotype Control ab208568) (Black) is used as isotype control. Unlabelled control: without incubation with primary antibody and secondary antibody (Blue).

  • Flow Cytometry - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668), expandable thumbnail

    Flow Cytometry - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668)

    Flow Cytometry analysis of HeLa (human cervix adenocarcinoma epithelial cell, Left) / A375 (human malignant melanoma epithelial cell, Right) labeling SOX10 with ab311668 at 1/500 dilution (0.1 μg)/Red. Cells were fixed with 4% Paraformaldehyde and permeabilised with 90% methanol. A Rabbit IgG monoclonal [EPR25A] - Isotype Control (Alexa Fluor® 594) (Alexa Fluor® 594 Rabbit IgG, monoclonal [EPR25A] - Isotype Control ab208568) (Black) is used as isotype control. Unlabelled control: without incubation with primary antibody and secondary antibody (Blue).

    Negative control: Hela.

  • Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668), expandable thumbnail

    Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668)

    Immunocytochemistry/Immunofluorescence analysis of B16-F0 (mouse melanoma epithelial-like cell) labeling SOX10 with ab311668 at 1/50 (10.0 μg/mL). Cells were fixed with 4% Paraformaldehyde and permeabilised with 0.1% TritonX-100. Alexa Fluor® 488 Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker ab195887 at 1/200 (2.5μg/mL) was as counterstain. Nuclear counterstain was DAPI.

    Confocal image showing nuclear staining in B16-F0 cells.
    Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

  • Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668), expandable thumbnail

    Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 594 Anti-SOX10 antibody [SP267] (ab311668)

    Immunocytochemistry/Immunofluorescence analysis of A375 (human malignant melanoma epithelial cell) labeling SOX10 with ab311668 at 1/50 (10.0 μg/mL). Cells were fixed with 4% Paraformaldehyde and permeabilised with 0.1% TritonX-100. Alexa Fluor® 488 Anti-alpha Tubulin antibody [DM1A] - Microtubule Marker ab195887 at 1/200 (2.5μg/mL) was as counterstain. Nuclear counterstain was DAPI.

    Confocal image showing nuclear staining in A375 cells.
    Negative control: HeLa (PMID:29315345)
    Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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