Alexa Fluor® 647 Anti-Galactosidase alpha antibody [EP5828(2)]
- RabMAb
- Recombinant
- What is this?
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Rabbit Recombinant Monoclonal Galactosidase alpha antibody - conjugated to Alexa Fluor® 647.
View Alternative Names
Alpha-galactosidase A, Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, Galactosylgalactosylglucosylceramidase GLA, Melibiase, GLA
Related conjugates and formulations (9)
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660 APC
APC Anti-Galactosidase alpha antibody [EP5828(2)]
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578 PE
PE Anti-Galactosidase alpha antibody [EP5828(2)]
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519 Alexa Fluor® 488
Alexa Fluor® 488 Anti-Galactosidase alpha antibody [EP5828(2)]
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617 Alexa Fluor® 594
Alexa Fluor® 594 Anti-Galactosidase alpha antibody [EP5828(2)]
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603 Alexa Fluor® 568
Alexa Fluor® 568 Anti-Galactosidase alpha antibody [EP5828(2)]
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565 Alexa Fluor® 555
Alexa Fluor® 555 Anti-Galactosidase alpha antibody [EP5828(2)]
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775 Alexa Fluor® 750
Alexa Fluor® 750 Anti-Galactosidase alpha antibody [EP5828(2)]
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Anti-Galactosidase alpha antibody [EP5828(2)]
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Anti-Galactosidase alpha antibody [EP5828(2)] - BSA and Azide free
Product details
Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The role of alpha-galactosidase involves the breakdown of complex carbohydrates particularly those containing alpha-galactosidic bonds. It does not operate as part of a complex but rather functions independently to cleave these specific bonds in glycolipids and glycoproteins. This activity is critical for degrading langerin and other gangliosides preventing the accumulation of these molecules in the lysosomes. By continuously performing this function alpha-galactosidase maintains glycosphingolipid homeostasis ensuring efficient cellular metabolism.
Pathways
The involvement of alpha-galactosidase in metabolic and lysosomal catabolic pathways is significant. One critical pathway is the glycolipid metabolism pathway where it acts alongside related enzymes such as beta-galactosidase. It also participates in the lysosomal degradation pathway working in conjunction with other lysosomal enzymes to prevent substrate buildup. The interaction with enzymes like lysosomal hydrolases ensures the proper breakdown of complex molecules into simpler ones that cells can utilize or excrete.
Product protocols
- Visit the General protocols
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Target data
Complementary Products
Cell Lines & Lysates
AB265563
Human GLA (Galactosidase alpha) knockout HeLa cell line
Advanced Validation
- 0
- 0
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com