JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB310226

Alexa Fluor® 647 Anti-S100 alpha 2 antibody [EPR5392]

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal S100 alpha 2/S100A2 antibody - conjugated to Alexa Fluor® 647.

View Alternative Names

S100L, S100A2, Protein S100-A2, CAN19, Protein S-100L, S100 calcium-binding protein A2

  • Unconjugated

    Anti-S100 alpha 2/S100A2 antibody [EPR5392]

  • 578 PE

    PE Anti-S100 alpha 2 antibody [EPR5392]

  • 660 APC

    APC Anti-S100 alpha 2 antibody [EPR5392]

  • 603 Alexa Fluor® 568

    Alexa Fluor® 568 Anti-S100 alpha 2/S100A2 antibody [EPR5392]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-S100 alpha 2 antibody [EPR5392]

  • HRP

    HRP Anti-S100 alpha 2 antibody [EPR5392]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-S100 alpha 2/S100A2 antibody [EPR5392]

  • Carrier free

    Anti-S100 alpha 2/S100A2 antibody [EPR5392] - BSA and Azide free

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-S100 alpha 2 antibody [EPR5392]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-S100 alpha 2 antibody [EPR5392]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR5392

Isotype

IgG

Conjugation

Alexa Fluor® 647

Excitation/Emission

Ex: 650nm, Em: 665nm

Carrier free

No

Applications

Antibody Labelling, Target Binding Affinity

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

You may be interested in:

AB314383

Human S100 alpha 2/S100A2 ELISA Kit

0

0 Reviews

View product

We recommend this product because it’s often used in the same experiment or related research.

We advise that you always check the datasheet to ensure it fits your experiments, or contact ourtechnical teamfor help.

style
left-column

Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 68% PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

S100 alpha 2 also known as S100A2 or CAN19 is a calcium-binding protein that plays a role in the regulation of cell functions. It's part of the S100 protein family and has a mass of approximately 11 kDa. S100A2 is expressed in a variety of tissues including epidermal cells and lung tissue suggesting its involvement in diverse cellular processes. The presence in these tissues indicates a potential role in both skin biology and respiratory system functions.
Biological function summary

S100A2 influences cell proliferation differentiation and apoptosis. It acts by modulating the activity of target proteins through a calcium-dependent mechanism. Though S100A2 is not known to form a complex with other proteins for its function it interacts with key cell growth regulators affecting cellular responses to external signals. The precise modulation of these processes implicates S100A2 in the maintenance of normal tissue homeostasis and cell cycle regulation.

Pathways

S100A2 participates in signal transduction pathways such as the MAPK/ERK and p53 pathways. In the MAPK/ERK pathway S100A2 regulates cell cycle progression and cellular responses to growth factors. Additionally in the p53 pathway S100A2 plays a role in apoptosis and tumor suppression. S100A2’s function links it to interaction with critical proteins such as p53 influencing both stress response and genomic stability.

S100A2 relates to cancer progression and pulmonary diseases. Altered expression levels of S100A2 have been observed in lung cancer and some skin cancers where it may act as a tumor suppressor. In pulmonary conditions its expression affects tissue responses under pathological states. The interaction of S100A2 with proteins like p53 in these disorders suggests a pivotal role in mediating stress responses and regulating tumor growth providing potential therapeutic targets.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
See full target information S100A2
style
left-column
style
left-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
style
left-column
style
right-column

Associated Products

Select an associated product type
Alternative Version
Primary Antibodies

AB247877

Anti-S100 alpha 2/S100A2 antibody [EPR5392] - BSA and Azide free

primary-antibodies

s100-alpha-2-s100a2-antibody-epr5392-bsa-and-azide-free-ab247877

5

(1 reviews)

style
bg-slate-100

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com