Anti-alpha 1a Adrenergic Receptor/ADRA1A antibody [S04-8B8]

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Alpha 1a Adrenergic Receptor plays a critical role in regulating smooth muscle contraction and blood vessel vasoconstriction. It forms an important part of the adrenergic receptor system which also includes alpha adrenergic receptors such as alpha 1b and alpha 1d subclasses. The activation of the alpha 1a receptor promotes vasoconstriction which contributes to blood pressure regulation. Additionally it is involved in modulating neurotransmitter release through its presence in nerve cells.

Pathways

Alpha 1a Adrenergic Receptor figures prominently in signaling pathways that manage cardiovascular functions. It is tightly associated with the GPCR signaling pathway which includes other adrenergic receptors and proteins like beta adrenergic receptors. Another significant pathway is the calcium signaling pathway where its impact on intracellular calcium plays a role in muscle contractions linking it to other proteins involved in the contraction machinery.