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AB24542

Anti-AMH antibody [5/6]

3

(2 Reviews)

|

(14 Publications)

Mouse Monoclonal AMH antibody. Suitable for IHC-P and reacts with Mouse samples. Cited in 14 publications. Immunogen corresponding to Synthetic Peptide within Human AMH aa 500 to C-terminus.

View Alternative Names

MIF, AMH, Anti-Muellerian hormone, Muellerian-inhibiting factor, Muellerian-inhibiting substance, MIS

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (AB24542)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (AB24542)

ab24542, at a dilution of 1/20 to 1/40, staining formalin fixed paraffin embedded ovary tissue from a 25 day old mouse by Immunohystochemistry.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5/6

Isotype

IgG1

Carrier free

No

Reacts with

Mouse

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human AMH aa 500 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P03971

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/40", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
Preservative: 0.09% Sodium azide Constituents: Tissue culture supernatant
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

The anti-Muellerian hormone (AMH) plays an important role in several reproductive functions (PubMed : 14742691, PubMed : 34155118, PubMed : 3754790, PubMed : 8469238). Anti-Muellerian hormone binds and activates AMHR2, its specific type-II receptor, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A) to regulate target gene expression through downstream SMAD protein signal transduction (PubMed : 20861221, PubMed : 34155118). Produced and secreted by Sertoli cells of the male fetus, anti-Muellerian hormone induces Muellerian duct regression during male fetal sexual differentiation (PubMed : 34155118, PubMed : 3754790, PubMed : 8469238). In female, it is produced by granulosa cells of the preantral and small antral follicles and acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles (PubMed : 14742691). Also plays a role in Leydig cell differentiation and function (By similarity).
See full target information AMH
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Publications (14)

Recent publications for all applications. Explore the full list and refine your search

BJOG : an international journal of obstetrics and gynaecology 132:107-119 PubMed39973029

2025

Effects of Gonadotropin-Releasing Hormone Analogues on Ovarian Function and Embryogenesis: A Cyclophosphamide-Induced Mouse Model Study.

Applications

Unspecified application

Species

Unspecified reactive species

Qiwang Lin,Mingzhu Cao,Zijin Xu,He Fei,Yunfeng Jin,Jianqiao Liu,Hua Jiang

EBioMedicine 97:104850 PubMed37898094

2023

Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice.

Applications

Unspecified application

Species

Unspecified reactive species

Mauro S B Silva,Laurine Decoster,Gaspard Delpouve,Tori Lhomme,Gaetan Ternier,Vincent Prevot,Paolo Giacobini

PeerJ 9:e11798 PubMed34322327

2021

Precocious puberty in male wild boars: a possible explanation for the dramatic population increase in Germany and Europe.

Applications

Unspecified application

Species

Unspecified reactive species

Claudia Maistrelli,Hanna Hüneke,Marion Langeheine,Oliver Keuling,Ursula Siebert,Ralph Brehm

Journal of gynecology obstetrics and human reproduction 50:102171 PubMed34048958

2021

Fertility in McCune Albright syndrome female: A case study focusing on AMH as a marker of ovarian dysfunction and a literature review.

Applications

Unspecified application

Species

Unspecified reactive species

Mikaël Agopiantz,Arthur Sorlin,Pierre Vabres,Bruno Leheup,Virginie Carmignac,Catherine Malaplate-Armand,Catherine Diligent,Céline Bonnet,Guillaume Gauchotte

BMC complementary medicine and therapies 21:90 PubMed33711998

2021

Evaluation of expression and serum concentration of anti-Mullerian hormone as a follicle growth marker following consumption of fennel and flaxseed extract in first-generation mice pups.

Applications

Unspecified application

Species

Unspecified reactive species

Fahimeh Pourjafari,Tahereh Haghpanah,Fariba Sharififar,Seyed Noreddin Nematollahi-Mahani,Ali Afgar,Massood Ezzatabadipour

Drug design, development and therapy 14:4975-4992 PubMed33239863

2020

Therapeutic Effects of Modified Gengnianchun Formula on Stress-Induced Diminished Ovarian Reserve Based on Experimental Approaches and Network Pharmacology.

Applications

Unspecified application

Species

Unspecified reactive species

Lingyun Gao,Yang Zhang,Huangfang Xu,Fangui Zhao,Wenjun Wang

Cells 9: PubMed32164318

2020

Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch.

Applications

Unspecified application

Species

Unspecified reactive species

Erika Hilbold,Ottmar Distl,Martina Hoedemaker,Sandra Wilkening,Rüdiger Behr,Aleksandar Rajkovic,Marion Langeheine,Kristina Rode,Klaus Jung,Julia Metzger,Ralph H J Brehm

eLife 8: PubMed31291191

2019

Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism.

Applications

Unspecified application

Species

Unspecified reactive species

Samuel Andrew Malone,Georgios E Papadakis,Andrea Messina,Nour El Houda Mimouni,Sara Trova,Monica Imbernon,Cecile Allet,Irene Cimino,James Acierno,Daniele Cassatella,Cheng Xu,Richard Quinton,Gabor Szinnai,Pascal Pigny,Lur Alonso-Cotchico,Laura Masgrau,Jean-Didier Maréchal,Vincent Prevot,Nelly Pitteloud,Paolo Giacobini

Gynecological endocrinology : the official journal 36:49-54 PubMed31269828

2019

Diminished ovarian reserve induced by chronic unpredictable stress in C57BL/6 mice.

Applications

Unspecified application

Species

Unspecified reactive species

Lingyun Gao,Fangui Zhao,Yang Zhang,Wenjun Wang,Qi Cao

Cellular physiology and biochemistry : internation 51:2341-2358 PubMed30537739

2018

Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaowei Nie,Youjin Dai,Yuan Zheng,Dan Bao,Qin Chen,Yuan Yin,Heling Fu,Daorong Hou
View all publications
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Product promise

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