Mouse Monoclonal AMH antibody. Suitable for IHC-P and reacts with Mouse samples. Cited in 12 publications. Immunogen corresponding to Synthetic Peptide within Human AMH aa 500 to C-terminus.
Images
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (AB24542), expandable thumbnail](https://content.abcam.com/products/images/amh-antibody-5-6-ab24542--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img77022.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (AB24542)")
Publications
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- PeerJ 9:e117982021Precocious puberty in male wild boars: a possible explanation for the dramatic population increase in Germany and Europe.Applications:Unspecified applicationReactive species:Unspecified reactive speciesClaudia Maistrelli,Hanna Hüneke,Marion Langeheine,Oliver Keuling,Ursula Siebert,Ralph BrehmPubMed 34322327
- Journal of gynecology obstetrics and human reproduction 50:1021712021Fertility in McCune Albright syndrome female: A case study focusing on AMH as a marker of ovarian dysfunction and a literature review.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMikaël Agopiantz,Arthur Sorlin,Pierre Vabres,Bruno Leheup,Virginie Carmignac,Catherine Malaplate-Armand,Catherine Diligent,Céline Bonnet,Guillaume GauchottePubMed 34048958
- BMC complementary medicine and therapies 21:902021Evaluation of expression and serum concentration of anti-Mullerian hormone as a follicle growth marker following consumption of fennel and flaxseed extract in first-generation mice pups.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFahimeh Pourjafari,Tahereh Haghpanah,Fariba Sharififar,Seyed Noreddin Nematollahi-Mahani,Ali Afgar,Massood EzzatabadipourPubMed 33711998
- Drug design, development and therapy 14:4975-49922020Therapeutic Effects of Modified Gengnianchun Formula on Stress-Induced Diminished Ovarian Reserve Based on Experimental Approaches and Network Pharmacology.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLingyun Gao et. al.PubMed 33239863
- Cells 9:2020Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch.Applications:Unspecified applicationReactive species:Unspecified reactive speciesErika Hilbold et. al.PubMed 32164318
- eLife 8:2019Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSamuel Andrew Malone et. al.PubMed 31291191
- Gynecological endocrinology : the official journal 36:49-542019Diminished ovarian reserve induced by chronic unpredictable stress in C57BL/6 mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLingyun Gao et. al.PubMed 31269828
- Cellular physiology and biochemistry : internation 51:2341-23582018Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaowei Nie et. al.PubMed 30537739
- The Journal of biological chemistry 286:23280-952011Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility.
- Endocrinology 147:3228-342006Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMarlies E Kevenaar et. al.PubMed 16556768
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: Tissue culture supernatant- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Synthetic Peptide within Human AMH aa 500 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link P03971
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Reactivity data
Select an application| IHC-P | |
|---|---|
| Mouse | Tested |
| Rat | Predicted |
| Cow | Predicted |
| Pig | Predicted |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/20.00000 - 1/40.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat, Cow, Pig | Dilution info - | Notes - |
Associated Products
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Target data
Function
Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation (PubMed:34155118, PubMed:3754790, PubMed:8469238). Also plays a role in Leydig cell differentiation and function (By similarity). In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles (PubMed:14742691). AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression (PubMed:20861221, PubMed:34155118).
Alternative names
MIF, AMH, Muellerian-inhibiting factor, Anti-Muellerian hormone, Muellerian-inhibiting substance, MIS
Recommended products
Mouse Monoclonal AMH antibody. Suitable for IHC-P and reacts with Mouse samples. Cited in 12 publications. Immunogen corresponding to Synthetic Peptide within Human AMH aa 500 to C-terminus.
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: Tissue culture supernatant- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Synthetic Peptide within Human AMH aa 500 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link P03971
- Clone number
- 5/6
- Purity
- Tissue culture supernatant
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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1 product image
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (ab24542), expandable thumbnail](https://content.abcam.com/products/images/amh-antibody-5-6-ab24542--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img77022.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (ab24542)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AMH antibody [5/6] (ab24542)
ab24542, at a dilution of 1/20 to 1/40, staining formalin fixed paraffin embedded ovary tissue from a 25 day old mouse by Immunohystochemistry.
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