Rabbit Recombinant Monoclonal Androgen Receptor antibody. N-terminal. Suitable for WB, IHC-P and reacts with Mouse, Rat, Human samples. Cited in 6 publications.
Images
![Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--western-blot-img19043.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img21184.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img38693.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img131937.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img138124.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (AB105225)")
Publications
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- Cancer medicine 12:10816-108282023Androgen promotes squamous differentiation of atypical cells in cervical intraepithelial neoplasia via an ELF3-dependent pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTakeo Matsumoto,Takuma Suzuki,Mitsuhiro Nakamura,Megumi Yamamoto,Takashi Iizuka,Masanori Ono,Kyosuke Kagami,Haruki Kasama,Tatsuhito Kanda,Yuya Sakai,Junpei Iwadare,Ayumi Matsuoka,Kayo Kayahashi,Kousho Wakae,Masamichi Muramatsu,Satoru Kyo,Yasuhiko Yamamoto,Yasunari Mizumoto,Takiko Daikoku,Hiroshi FujiwaraPubMed 36951594
- Small methods 7:e22012932022PROTAC Degraders of Androgen Receptor-Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRuxuan Wang,Tengjiang Zhong,Qiong Bian,Sai Zhang,Xiaolu Ma,Liming Li,Yihua Xu,Yueting Gu,Anran Yuan,Weitong Hu,Chong Qin,Jianqing GaoPubMed 36538748
- iScience 24:1023032021Myofiber androgen receptor increases muscle strength mediated by a skeletal muscle splicing variant of Mylk4.Applications:Unspecified applicationReactive species:Unspecified reactive speciesIori Sakakibara,Yuta Yanagihara,Koichi Himori,Takashi Yamada,Hiroshi Sakai,Yuichiro Sawada,Hirotaka Takahashi,Noritaka Saeki,Hiroyuki Hirakawa,Atsushi Yokoyama,So-Ichiro Fukada,Tatsuya Sawasaki,Yuuki ImaiPubMed 33870126
- Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 33:1056-10642020Immunohistochemical analysis of IDH2 R172 hotspot mutations in breast papillary neoplasms: applications in the diagnosis of tall cell carcinoma with reverse polarity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFresia Pareja,Edaise M da Silva,Denise Frosina,Felipe C Geyer,John R Lozada,Thais Basili,Arnaud Da Cruz Paula,Elaine Zhong,Fatemeh Derakhshan,Timothy D'Alfonso,Hannah Y Wen,Dilip D Giri,Malcolm M Hayes,Gregor Krings,Rohit Bhargava,Juan P Palazzo,Emad A Rakha,Syed A Hoda,Melinda E Sanders,Laura C Collins,Stuart J Schnitt,Yunn-Yi Chen,Britta Weigelt,Achim A Jungbluth,Jorge S Reis-Filho,Edi BrogiPubMed 31896809
- Oncotarget 9:35327-353422018Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAmro Aboukameel et. al.PubMed 30450161
- European archives of oto-rhino-laryngology : offic 275:1885-18922018Salivary duct carcinoma: evaluation of treatment and outcome in a tertiary referral institute.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnn-Jean C C Beck et. al.PubMed 29785551
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.6
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Tested | Tested |
| Rat | Tested | Tested |
| Dog | Predicted | Predicted |
| Pig | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 0.22 µg/mL | Notes - |
Species Rat | Dilution info 0.22 µg/mL | Notes - |
Species Human | Dilution info 1.55 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Dog, Pig | Dilution info - | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/400 | Notes Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
Species Rat | Dilution info 1/400 | Notes Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
Species Human | Dilution info 1/400 | Notes Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Dog, Pig | Dilution info - | Notes - |
Associated Products
Select an associated product type
8 products for Alternative Product
Target data
Function
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849). Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. Isoform 3. Lacks the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones. Isoform 4. Lacks the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.
Alternative names
DHTR, NR3C4, AR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Recommended products
Rabbit Recombinant Monoclonal Androgen Receptor antibody. N-terminal. Suitable for WB, IHC-P and reacts with Mouse, Rat, Human samples. Cited in 6 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.6
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- SP107
- Purification technique
- Affinity purification Protein A/G
- Concentration
- Purification notes
Purified from TCS by protein A/G.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
The androgen receptor (AR) also known as NR3C4 functions mechanically as a type of nuclear receptor that is activated by binding androgens including testosterone and dihydrotestosterone. The AR has a molecular weight of approximately 110 kDa. It is expressed in various tissues notably in the prostate skeletal muscle and certain areas of the brain. Within cells AR is usually located in the cytoplasm when unbound and translocates to the nucleus upon activation by its ligands.
- Biological function summary
AR interacts with androgen hormones to regulate gene expression. It forms a complex with coactivators and corepressors to modulate transcription of target genes involved in male sexual development and reproductive function. AR plays an important role in the development and maintenance of male characteristics and reproductive activity. Its expression impacts cellular processes such as proliferation differentiation and apoptosis.
- Pathways
AR is intricately involved in the androgen signaling pathway which affects the regulation of genes related to male sexual characteristics. It also plays a part in the PI3K/Akt pathway influencing cell growth and survival. The AR pathway interacts with proteins such as estrogen receptors to mediate cross-talk between hormonal pathways highlighting its broad biological impacts.
- Associated diseases and disorders
AR has a significant connection to prostate cancer where it drives tumor growth and progression. Mutations and overexpression of the androgen receptor are often observed in prostate cancer cells. Another condition linked to AR is androgen insensitivity syndrome where mutations in the AR gene result in partial or complete inability of cells to respond to androgenic hormones. In these conditions AR antagonists like bicalutamide are often used as treatment inhibiting the receptor's activity to manage disease progression.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
22 product images
![Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--western-blot-img19043.jpg "Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Blocking/Diluting buffer and concentration: 5% NFDM /TBST
All lanes: Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225) at 1.55 µg
Lane 1: LnCAP (Human prostate carcinoma epithelial cell) cell lysate at 20 µg
Lane 2: DU 145 (Human prostate carcinoma epithelial cell) cell lysate at 20 µg
Lane 3: Mouse testis tissue lysate at 20 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 0.05 µg/mL
Predicted band size: 99 kDa
Observed band size: 120 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img21184.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Rat testis tissue sections labeling Androgen Receptor with Purified ab105225 at 1/400 dilution (0.37 µg/ml). Heat mediated antigen retrieval was performed Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0, epitope retrieval solution 1) for 30mins. Rabbit specific IHC polymer detection kit HRP/DAB (Rabbit specific IHC polymer detection kit HRP/DAB ab209101) was used as the secondary antibody. Negative control: PBS instead of the primary antibody. Hematoxylin was used as a counterstain.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img38693.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Mouse testis tissue sections labeling Androgen Receptor with Purified ab105225 at 1/400 dilution (0.37 µg/ml). Heat mediated antigen retrieval was performed Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0, epitope retrieval solution 1) for 30mins. Rabbit specific IHC polymer detection kit HRP/DAB (Rabbit specific IHC polymer detection kit HRP/DAB ab209101) was used as the secondary antibody. Negative control: PBS instead of the primary antibody. Hematoxylin was used as a counterstain.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img131937.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human prostate cancer tissue sections labeling Androgen Receptor with Purified ab105225 at 1/400 dilution (0.37 µg/ml). Heat mediated antigen retrieval was performed Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0, epitope retrieval solution 1) for 30mins. Rabbit specific IHC polymer detection kit HRP/DAB (Rabbit specific IHC polymer detection kit HRP/DAB ab209101) was used as the secondary antibody. Negative control: PBS instead of the primary antibody. Hematoxylin was used as a counterstain.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img138124.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human ovarian adenocarcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img126366.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human prostate carcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136765.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human pancreatic adenocarcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img137348.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human breast ductal carcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img14199.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human skin squamous cell carcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img112558.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human uterus tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img65815.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human breast tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136815.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human testis tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img135230.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human cervix tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img138872.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human placenta tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img104096.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human prostate tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img139227.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human bladder transitional cell carcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img139515.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human hepatocellular carcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136639.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human endometrial adenocarcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img60924.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human lung adenocarcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img97960.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human lung squamous cell carcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136869.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Formalin-fixed, paraffin-embedded human prostate adenocarcinoma tissue stained for Androgen Receptor with ab105225 at 1/400 dilution in immunohistochemical analysis.
![Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--western-blot-img431262.jpg "Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)
Blocking and dilution buffer and concentration: 5% NFDM/TBST.
Anti-GAPDH antibody [EPR16891] - Loading Control ab181602 was used as a GAPDH loading control.
All lanes: Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225) at 1/1000 dilution
Lane 1: Mouse liver tissue lysate at 20 µg
Lane 2: Rat liver tissue lysate at 20 µg
Lane 3: Mouse testis tissue lysate at 20 µg
Lane 4: Rat testis tissue lysate at 20 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/20000 dilution
Predicted band size: 99 kDa
Observed band size: 110 kDa
Exposure time: 60s
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img126366.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136765.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img137348.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img14199.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img112558.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img65815.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136815.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img135230.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img138872.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img104096.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img139227.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img139515.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136639.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img60924.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img97960.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img136869.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
![Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225), expandable thumbnail](https://content.abcam.com/products/images/androgen-receptor-antibody-sp107-n-terminal-ab105225--western-blot-img431262.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Androgen Receptor antibody [SP107] - N-terminal (ab105225)")
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