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AB281241

Anti-ANGPTL6 antibody [EPR23076-12] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal ANGPTL6 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

View Alternative Names

AGF, ARP5, UNQ152/PRO178, ANGPTL6, Angiopoietin-related protein 6, Angiopoietin-like protein 6, Angiopoietin-related growth factor, Angiopoietin-related protein 5

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Sandwich ELISA - Anti-ANGPTL6 antibody [EPR23076-12] - BSA and Azide free (Capture) (AB281241)
  • sELISA

Lab

Sandwich ELISA - Anti-ANGPTL6 antibody [EPR23076-12] - BSA and Azide free (Capture) (AB281241)

Sandwich ELISA of ab253681 with the capture antibody ab281241 dilution at 2 µg/mL and detector antibody ab281091 dilution at 0.5 µg/mL.

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR23076-12

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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Product details

ab281241 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human Angptl6. The recommended pair for sandwich ELISA is:
Capture: ab281241, Human Angptl6 Capture Antibody (unconjugated)
Detector: ab281091, Human Angptl6 Detector Antibody (unconjugated)
The reference range value is 39.1-5000 pg/mL.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ANGPTL6 also known as Angiopoietin-like 6 is a protein involved in modulating several physiological processes. The protein has a molecular weight of approximately 54 kDa. ANGPTL6 is expressed in various tissues such as the liver heart and adipose tissue indicating its involvement in systemic functions. The protein is a secretory glycoprotein influencing various cellular mechanisms due to its diverse localization.
Biological function summary

ANGPTL6 functions in the regulation of metabolic processes including glucose and lipid metabolism. It is not part of a larger complex but acts individually in its biological roles. ANGPTL6 has been shown to improve insulin sensitivity and promote energy expenditure. Through these mechanisms it plays an essential role in maintaining metabolic homeostasis and supports cellular health.

Pathways

ANGPTL6 significantly interacts within metabolic and cardiovascular pathways. The protein influences the insulin signaling pathway and is connected to proteins like AKT and PI3K integral components of metabolic regulation. ANGPTL6 also affects pathways involved in angiogenesis providing cross-talk with vascular endothelial growth factor (VEGF)-mediated signaling an important aspect of cardiovascular health.

ANGPTL6 has connections to metabolic syndrome and obesity-related conditions. Its role in maintaining insulin sensitivity and influencing glucose metabolism links it to type 2 diabetes. By modulating pathways related to lipid balance ANGPTL6 also relates to cardiovascular diseases. Associations with proteins such as VEGF and AKT elucidate its involvement in vascular health and metabolic disorders.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
See full target information ANGPTL6
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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