JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB229965

Anti-ANP32D antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal ANP32D antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ANP32D.

View Alternative Names

PP32R2, ANP32D, Acidic leucine-rich nuclear phosphoprotein 32 family member D, Phosphoprotein 32-related protein 2, Tumorigenic protein pp32r2

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-ANP32D antibody (AB229965)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ANP32D antibody (AB229965)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for ANP32D (green) using ab229965 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® congugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ANP32D antibody (AB229965)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ANP32D antibody (AB229965)

Paraffin-embedded human gastric cancer tissue stained for ANP32D using ab229965 at 1/100 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Full Length Protein corresponding to Human ANP32D.

O95626

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/100", "ICCIF-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity > 95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ANP32D also known as acidic nuclear phosphoprotein 32 family member D is a protein involved in various cellular processes. It has a molecular weight of approximately 32 kDa. The protein is expressed broadly with notable levels in the nucleus and cytoplasm of diverse cell types. ANP32D functions in modulating chromatin dynamics and may influence transcriptional regulation and cellular signaling. Additionally it contributes to cellular processes like apoptosis and cell cycle progression due to its interaction with multiple signaling molecules and chromatin modifiers.
Biological function summary

Proteins like ANP32D are important in the regulation of gene expression and maintenance of chromatin structure. It often functions as part of larger protein complexes integrating signals that dictate chromatin remodeling and transcriptional responses. ANP32D interacts with histone-binding proteins contributing to the dynamic changes in chromatin architecture required for gene expression and cellular responses. Its role in such complexes highlights its impact on processes like embryonic development and cellular differentiation.

Pathways

Various proteins work together with ANP32D impacting important biological systems like the MAPK signaling pathway and the apoptosis regulation pathway. ANP32D interacts with factors like histone deacetylases playing a part in signal transduction and transcriptional repression. The protein's involvement in these pathways suggests that it helps mediate cellular responses to external stimuli and internal cues coordinating cellular growth division and programmed cell death.

Research has linked ANP32D to cancer and neurodegenerative conditions. Its expression often changes in tumor tissues associating ANP32D with cancer progression and development. Altered levels of ANP32D as well as its interaction with proteins like PP2A can impact cellular proliferation and survival contributing to oncogenic processes. Its potential role in neurodegenerative disorders though less explored suggests ANP32D's involvement in cellular pathways affecting neuron survival and function highlighting its importance in disease mechanisms.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information ANP32D
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Reproductive sciences (Thousand Oaks, Calif.) 32:716-727 PubMed39934615

2025

MEIS1-mediated Apoptosis via TNFR1 in Endometriosis.

Applications

Unspecified application

Species

Unspecified reactive species

Wenwen Wang,Fangfang Fu,Yan Li,Sha Li,Ming Yuan,Tian Wang,Wu Ren,Jia Wei,Dan Chen,Shixuan Wang,Xiangyi Ma,Zhangying Wu
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB184699

Anti-ERK1 + ERK2 antibody [EPR17526]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-ERK1 + ERK2 antibody [EPR17526] (AB184699)

  • 5
  • 1
Primary Antibodies

AB215715

Anti-TGF beta 1 antibody [EPR21143]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Western blot - Anti-TGF beta 1 antibody [EPR21143] (AB215715)

  • 5
  • 6
Primary Antibodies

AB68153

Anti-STAT3 antibody [EPR787Y]

KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Western blot - Anti-STAT3 antibody [EPR787Y] (AB68153)

  • 4
  • 10
Primary Antibodies

AB259657

Anti-NT-proBNP antibody [EPR20260-209] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-NT-proBNP antibody [EPR20260-209] - BSA and Azide free (Capture) (AB259657)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com