AB25567

APC Anti-CD40 antibody [1C10]

Name: APC Anti-CD40 antibody [1C10] (ab25567) | Abcam
Brand: Abcam Limited
SKU: AB25567
Price: 320 USD
Availability: InStock

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(1 Publication)

Rat Monoclonal CD40 antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CD40.

View Alternative Names

CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40

1 Images

Flow Cytometry - APC Anti-CD40 antibody [1C10] (AB25567)

Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-CD40 antibody [1C10] (AB25567)

Flow cytometric analysis of BALB/c mouse splenocytes labeling CD40 using ab25567 at 0.1 μg/10⁶ cells in 100 μL. CD3ε is labeled using a Rat Anti-Mouse CD3ε (FITC) antibody.

Unconjugated

Anti-CD40 antibody [1C10]
578 PE

PE Anti-CD40 antibody [1C10]

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

1C10

Isotype

IgG2a

Light chain type

kappa

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

Reacts with

Mouse

Applications

Flow Cyt

applications

Immunogen

Recombinant Fragment Protein within Human CD40. The exact immunogen used to generate this antibody is proprietary information.

P25942

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>" } } }

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Product details

This agonistic antibody closely resembles the gp39/CD40 ligand in it's ability to stimulate the proliferation of small, resting B lymphocytes in the absence of other cofactors. This antibody has been shown to be useful in studies of the 'in vitro' induction of proliferation of mature B lymphocytes.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification

Storage buffer

pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Store in the dark

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for TNFSF5/CD40LG (PubMed : 31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

See full target information CD40

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Neuroscience letters 470:19-23 PubMed20035831

2009

TNF-alpha receptor 1 deficiency reduces antigen-presenting capacity of Schwann cells and ameliorates experimental autoimmune neuritis in mice.

Applications

Flow Cyt

Species

Mouse

Xi-Jing Mao,Xing-Mei Zhang,Hong-Liang Zhang,Hernan Concha Quezada,Eilhard Mix,Xin Yang,Bengt Winblad,Abdu Adem,Jie Zhu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

APC Anti-CD40 antibody [1C10]

Flow Cytometry - APC Anti-CD40 antibody [1C10] (AB25567)

Related conjugates and formulations (2)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (1)

Product promise