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AB95725

APC Anti-CD41 antibody [MWReg30]

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(4 Publications)

Rat Monoclonal CD41 antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 4 publications. Immunogen corresponding to Cell preparation containing Itga2b protein.

View Alternative Names

CD41, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb, Itga2b

1 Images
Flow Cytometry - APC Anti-CD41 antibody [MWReg30] (AB95725)
  • Flow Cyt

Unknown

Flow Cytometry - APC Anti-CD41 antibody [MWReg30] (AB95725)

Staining of mouse platelets with anti-Mouse CD61 PE and 0.125µg of Rat IgG1 kappa Isotype Control APC (left) or 0.125 µg of ab95725 (right).

  • Carrier free

    Anti-CD41 antibody [MWReg30] - Low endotoxin, Azide free

  • Unconjugated

    Anti-CD41 antibody [MWReg30]

  • 578 PE

    PE Anti-CD41 antibody [MWReg30]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD41 antibody [MWReg30]

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

MWReg30

Isotype

IgG1

Light chain type

kappa

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing Itga2b protein. The exact immunogen used to generate this antibody is proprietary information.

Q9QUM0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.125-0.25 µg for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p>A final volume of 100μl is recommended.</p><p><a href='/en-us/products/unavailable/rat-igg1-kappa-monoclonal-klhg1-2-2-apc-isotype-control-ab154433'>ab154433</a> - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }
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We recommend this product because it’s often used in the same experiment or related research.

We advise that you always check the datasheet to ensure it fits your experiments, or contact ourtechnical teamfor help.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.1% Gelatin
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
See full target information Itga2b
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Proceedings of the National Academy of Sciences of the United States of America 102:134-9 PubMed15623562

2004

Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin.

Applications

Flow Cyt

Species

Unspecified reactive species

Julien Y Bertrand,Sébastien Giroux,Rachel Golub,Michèle Klaine,Abdelali Jalil,Laurent Boucontet,Isabelle Godin,Ana Cumano

Development (Cambridge, England) 129:2003-13 PubMed11934866

2002

Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells.

Applications

Flow Cyt

Species

Unspecified reactive species

Maria Teresa Mitjavila-Garcia,Michel Cailleret,Isabelle Godin,Maria Manuela Nogueira,Karine Cohen-Solal,Valérie Schiavon,Yann Lecluse,Françoise Le Pesteur,Anne Hélène Lagrue,William Vainchenker

Blood 98:1095-9 PubMed11493456

2001

Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia.

Applications

Unspecified application

Species

Unspecified reactive species

J L Teeling,T Jansen-Hendriks,T W Kuijpers,M de Haas,J G van de Winkel,C E Hack,W K Bleeker

Blood 94:684-93 PubMed10397735

1999

Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.

Applications

Flow Cyt

Species

Unspecified reactive species

B Nieswandt,B Echtenacher,F P Wachs,J Schröder,J E Gessner,R E Schmidt,G E Grau,D N Männel
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Associated Products

Select an associated product type
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Alternative Version
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Alternative Version
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