AB139364

APC Anti-CD90 / Thy1 antibody [5E10]

Name: Anti-CD90 / Thy1 APC antibody [5E10] (ab139364) IgG1 | Abcam
Brand: Abcam Limited
SKU: AB139364
Price: 110 USD
Availability: InStock
Rating: 1 (1 reviews)

(1 Review)

(12 Publications)

Mouse Monoclonal CD90 / Thy1 antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Human samples. Cited in 12 publications. Immunogen corresponding to Cell preparation containing THY1 protein.

View Alternative Names

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - APC Anti-CD90 / Thy1 antibody [5E10] (AB139364)

Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-CD90 / Thy1 antibody [5E10] (AB139364)

Flow cytometry analysis (surface staining) of Jurkat cells (red) and SP2 cells (blue) labeling CD90 with ab139364.

Unconjugated

Anti-CD90 / Thy1 antibody [5E10]
519 FITC

FITC Anti-CD90 / Thy1 antibody [5E10]
695 PerCP/Cy5.5®

PerCP/Cy5.5® Anti-CD90 / Thy1 antibody [5E10]
667 PE/Cy5®

PE/Cy5® Anti-CD90 / Thy1 antibody [5E10]
578 PE

PE Anti-CD90 / Thy1 antibody [5E10]
785 APC/Cy7®

APC/Cy7® Anti-CD90 / Thy1 antibody [5E10]
Biotin

Biotin Anti-CD90 / Thy1 antibody [5E10]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5E10

Isotype

IgG1

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>10 μl reagent / 100 μl of whole blood or 10<sup>6</sup> cells in a suspension.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Size-exclusion chromatography

Storage buffer

pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

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Publications (12)

Recent publications for all applications. Explore the full list and refine your search

Animals : an open access journal from MDPI 13: PubMed37627392

2023

Isolation of Vascular Wall Mesenchymal Stem Cells from the Thoracic Aorta of Adult Göttingen Minipigs: A New Protocol for the Simultaneous Endothelial Cell Collection.

Applications

Unspecified application

Species

Unspecified reactive species

Chiara Bernardini,Debora La Mantia,Roberta Salaroli,Domenico Ventrella,Alberto Elmi,Augusta Zannoni,Monica Forni

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 166:161-167 PubMed34747415

2021

A comparative study on the secretion of various cytokines by pulp stem cells at different passages and their neurogenic potential.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Yan,Ola A Nada,Ling-Ling Fu,Dong-Zhen Li,Hong-Chao Feng,Li-Ming Chen,Martin Gosau,Reinhard E Friedrich,Ralf Smeets

Biomedical papers of the Medical Faculty of the Un : PubMed33325456

2020

Compare features of human dental pulp cells cultured from pulp tissues with and without cryopreservation.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Yan,Ola A Nada,Ralf Smeets,Martin Gosau,Reinhard E Friedrich,Lan Kluwe

In vivo (Athens, Greece) 34:2363-2370 PubMed32871761

2020

Expansion of Human Dental Pulp Cells Under Different Cryopreservation Conditions.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Yan,Ola A Nada,Lan Kluwe,Martin Gosau,Ralf Smeets,Reinhard E Friedrich

International journal of molecular medicine 45:897-909 PubMed31985015

2020

Bidirectional ephrinB2‑EphB4 signaling regulates the osteogenic differentiation of canine periodontal ligament stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Shaoyue Zhu,Zongxiang Liu,Changyong Yuan,Yifan Lin,Yanqi Yang,Haiming Wang,Chengfei Zhang,Penglai Wang,Min Gu

World journal of gastroenterology 25:4892-4903 PubMed31543681

2019

effect of vascular wall stromal cells secretome on enteric ganglia.

Applications

Unspecified application

Species

Unspecified reactive species

Giovanni Dothel,Chiara Bernardini,Augusta Zannoni,Maria Rosaria Spirito,Roberta Salaroli,Maria Laura Bacci,Monica Forni,Fabrizio De Ponti

In vitro cellular & developmental biology. Animal 55:17-24 PubMed30456456

2018

Butyric acid induces spontaneous adipocytic differentiation of porcine bone marrow-derived mesenchymal stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Benedetta Tugnoli,Chiara Bernardini,Monica Forni,Andrea Piva,Chad H Stahl,Ester Grilli

Stem cells translational medicine 7:360-372 PubMed29457376

2018

Delivery of Allogeneic Adipose Stem Cells in Polyethylene Glycol-Fibrin Hydrogels as an Adjunct to Meshed Autografts After Sharp Debridement of Deep Partial Thickness Burns.

Applications

ICC/IF

Species

Pig

David M Burmeister,Randolph Stone,Nicole Wrice,Alfred Laborde,Sandra C Becerra,Shanmugasundaram Natesan,Robert J Christy

Stem cells international 2017:1836960 PubMed28539939

2017

Quantitative Assessment of Optimal Bone Marrow Site for the Isolation of Porcine Mesenchymal Stem Cells.

Applications

Flow Cyt

Species

Pig

J S McDaniel,B Antebi,M Pilia,B J Hurtgen,S Belenkiy,C Necsoiu,L C Cancio,C R Rathbone,A I Batchinsky

American journal of physiology. Cell physiology 309:C320-31 PubMed26135800

2015

In vitro differentiation of porcine aortic vascular precursor cells to endothelial and vascular smooth muscle cells.

Applications

Flow Cyt

Species

Human

Andrea Zaniboni,Chiara Bernardini,Martina Bertocchi,Augusta Zannoni,Francesca Bianchi,Giancarlo Avallone,Chiara Mangano,Giuseppe Sarli,Laura Calzà,Maria Laura Bacci,Monica Forni

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

APC Anti-CD90 / Thy1 antibody [5E10]

Flow Cytometry - APC Anti-CD90 / Thy1 antibody [5E10] (AB139364)

Related conjugates and formulations (7)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (12)

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