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AB272351

APC/Cy7® Anti-CD90 / Thy1 antibody [5E10]

5

(2 Reviews)

|

(2 Publications)

Mouse Monoclonal CD90 / Thy1 antibody - conjugated to APC/Cy7®. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing THY1 protein.

View Alternative Names

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

2 Images
Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)

Flow cytometric analysis of Jurkat cells labeling CD90 with ab272351 at 4μl reagent per milion cells in 100 μl of cell suspension.

Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD90 / Thy1 antibody [5E10] (AB272351)

Separation of Jurkat cells (Red) from SP2 cells (dashed) in flow cytometric analysis labeling CD90 using ab272351. (4 μl reagent per milion cells in 100 μl of cell suspension).

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5E10

Isotype

IgG1

Conjugation

APC/Cy7®

Excitation/Emission

Ex: 650nm, Em: 785nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>" } } }
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Product details

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Purification notes
Purified from TCS.
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).
Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
See full target information THY1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Advanced healthcare materials 12:e2202550 PubMed36527264

2022

Toward 3D Bioprinting of Osseous Tissue of Predefined Shape Using Single-Matrix Cell-Bioink Constructs.

Applications

Unspecified application

Species

Unspecified reactive species

Yawei Gu,Sebastien Pigeot,Lucas Ahrens,Fabian Tribukait-Riemenschneider,Melika Sarem,Francine Wolf,Andres García-García,Andrea Barbero,Ivan Martin,V Prasad Shastri

Journal of extracellular biology 1:e39 PubMed38939527

2022

Liver cancer cells with nuclear MET overexpression release translation regulatory protein-enriched extracellular vesicles exhibit metastasis promoting activity.

Applications

Unspecified application

Species

Unspecified reactive species

Sze Keong Tey,Samuel Wan Ki Wong,Cherlie Lot Sum Yeung,Jason Ying Ki Li,Xiaowen Mao,Clive Yik Sham Chung,Judy Wai Ping Yam
View all publications
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