AB25485

APC Anti-IL-2 Receptor alpha antibody [3C7]

Name: Anti-IL-2 Receptor alpha APC antibody [3C7] (ab25485) IgG2b | Abcam
Brand: Abcam Limited
SKU: AB25485
Price: 535 USD
Availability: InStock

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(2 Publications)

Rat Monoclonal IL2RA antibody - conjugated to APC. Suitable for IHC-Fr, Flow Cyt and reacts with Mouse samples. Cited in 2 publications.

View Alternative Names

CD25, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, IL2RA

1 Images

Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [3C7] (AB25485)

Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [3C7] (AB25485)

C57BL/6 mouse cytotoxic T lymphocyte cell line CTLL-2 was stained with Rat Anti- Mouse CD25-APC (ab25485). The grey peak represents an isotype control. The purple peak represents the positive dataset.

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

3C7

Isotype

IgG2b

Light chain type

kappa

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

Reacts with

Mouse

Applications

Flow Cyt, IHC-Fr

applications

Specificity

ab25485 recognises low affinity alpha chain IL-2 receptor (MW 55 kDa) (IL-2R alpha).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.3 µg for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification

Storage buffer

pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Store in the dark

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

See full target information IL2RA

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 13:160 PubMed35181676

2022

HOXA-AS2 contributes to regulatory T cell proliferation and immune tolerance in glioma through the miR-302a/KDM2A/JAG1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Chuanhong Zhong,Bei Tao,Xianglong Li,Wei Xiang,Lilei Peng,Tangming Peng,Ligang Chen,Xiangguo Xia,Jian You,Xiaobo Yang

Blood 115:3570-9 PubMed20194896

2010

The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.

Applications

Flow Cyt

Species

Mouse

Adelheid Bursen,Karen Schwabe,Brigitte Rüster,Reinhard Henschler,Martin Ruthardt,Theo Dingermann,Rolf Marschalek

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

APC Anti-IL-2 Receptor alpha antibody [3C7]

Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [3C7] (AB25485)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (2)

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Product promise