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AB210330

APC Anti-IL-2 Receptor alpha antibody [PC61.5]

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(4 Publications)

Rat Monoclonal IL2RA antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 4 publications.

View Alternative Names

CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55

1 Images
Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210330)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210330)

Flow Cytometry analysis of C57Bl/6 splenocytes labeling IL-2 Recepter alpha with ab210330 at 0.125 μg (right panel) or 0.125 μg Allophycocyanin Rat IgG1 (left panel). Counterstain : FITC Anti-Mouse CD4.

  • Carrier free

    Anti-IL-2 Receptor alpha antibody [PC61.5] - Low endotoxin, Azide free

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

PC61.5

Isotype

IgG1

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

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Alternative Products

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Primary Antibodies

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Primary Antibodies

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Primary Antibodies

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Complementary Products

Assay Kits

AB267643

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Primary Antibodies

AB277275

Alexa Fluor® 488 Anti-CD4 antibody [EPR19514]

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Primary Antibodies

AB210232

PE/Cy7® Anti-FOXP3 antibody [3G3]

Flow Cytometry (Intracellular) - PE/Cy7® Anti-FOXP3 antibody [3G3] (AB210232)

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Primary Antibodies

AB237365

Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769] (AB237365)

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Primary Antibodies

AB34722

FITC Anti-CD3 antibody [CD3-12]

Lab Essentials

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use at 0.125 μg/test</p>" } } }
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Product details

This antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25-.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Purification notes
Purified from tissue culture supernatant and conjugated under optimal conditions, with unreacted dye removed from the preparation.
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
See full target information Il2ra
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Advances in cancer biology - metastasis 7: PubMed37593105

2023

Benzophenone-3 exposure alters composition of tumor infiltrating immune cells and increases lung seeding of 4T1 breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Stephanie M Morin,Kelly J Gregory,Brenda Medeiros,Tigist Terefe,Reyhane Hoshyar,Ahmed Alhusseiny,Shiuan Chen,Richard C Schwartz,D Joseph Jerry,Laura N Vandenberg,Sallie S Schneider

Experimental and therapeutic medicine 25:271 PubMed37206552

2023

Changes in the balance of Th17/Treg cells and oxidative stress markers in patients with HIV‑associated pulmonary tuberculosis who develop IRIS.

Applications

Unspecified application

Species

Unspecified reactive species

Long Wen,Lei Shi,Shan-Shan Wan,Tao Xu,Lei Zhang,Zhi-Guo Zhou

International journal of molecular medicine 48: PubMed34036377

2021

Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis.

Applications

Unspecified application

Species

Unspecified reactive species

Can Cui,Dengwen Zhang,Ke Sun,Haifeng Li,Liqian Xu,Gen Lin,Yuanbo Guo,Jiaqi Hu,Jieyuan Chen,Lidan Nong,Yujin Cai,Dongnan Yu,Wei Yang,Peng Wang,Yi Sun

Frontiers in immunology 11:1934 PubMed33013847

2020

Mechanisms of M2 Macrophage-Derived Exosomal Long Non-coding RNA PVT1 in Regulating Th17 Cell Response in Experimental Autoimmune Encephalomyelitisa.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Wu,Jinjin Xia,Donghui Li,Ying Kang,Wei Fang,Peng Huang
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
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