Rat Monoclonal IL2RA antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 3 publications.
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![Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210330), expandable thumbnail](https://content.abcam.com/products/images/apc-il-2-receptor-alpha-antibody-pc615-ab210330--flow-cytometry-img86541.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210330)")
Publications
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- Advances in cancer biology - metastasis 7:2023Benzophenone-3 exposure alters composition of tumor infiltrating immune cells and increases lung seeding of 4T1 breast cancer cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesStephanie M Morin,Kelly J Gregory,Brenda Medeiros,Tigist Terefe,Reyhane Hoshyar,Ahmed Alhusseiny,Shiuan Chen,Richard C Schwartz,D Joseph Jerry,Laura N Vandenberg,Sallie S SchneiderPubMed 37593105
- International journal of molecular medicine 48:2021Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCan Cui,Dengwen Zhang,Ke Sun,Haifeng Li,Liqian Xu,Gen Lin,Yuanbo Guo,Jiaqi Hu,Jieyuan Chen,Lidan Nong,Yujin Cai,Dongnan Yu,Wei Yang,Peng Wang,Yi SunPubMed 34036377
- Frontiers in immunology 11:19342020Mechanisms of M2 Macrophage-Derived Exosomal Long Non-coding RNA PVT1 in Regulating Th17 Cell Response in Experimental Autoimmune Encephalomyelitisa.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLei Wu et. al.PubMed 33013847
Key facts
- Isotype
- IgG1
- Host species
- Rat
- Conjugation
- APC
- Excitation/Emission
- Ex: 650nm, Em: 660nm
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin- Form
- Liquid
- Clonality
- Monoclonal
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Mouse | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes Use at 0.125 μg/test |
Associated Products
Select an associated product type
3 products for Alternative Version
2 products for Alternative Product
Target data
Function
Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Alternative names
CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55
Recommended products
Rat Monoclonal IL2RA antibody - conjugated to APC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 3 publications.
Key facts
- Isotype
- IgG1
- Host species
- Rat
- Conjugation
- APC
- Excitation/Emission
- Ex: 650nm, Em: 660nm
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin- Form
- Liquid
- Clonality
- Monoclonal
- Clone number
- PC61.5
- Purification technique
- Affinity purification
- Concentration
- Purification notes
Purified from tissue culture supernatant and conjugated under optimal conditions, with unreacted dye removed from the preparation.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Store in the dark
Notes
This antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25-.
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Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
![Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (ab210330), expandable thumbnail](https://content.abcam.com/products/images/apc-il-2-receptor-alpha-antibody-pc615-ab210330--flow-cytometry-img86541.jpg "Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (ab210330)")
Flow Cytometry - APC Anti-IL-2 Receptor alpha antibody [PC61.5] (ab210330)
Flow Cytometry analysis of C57Bl/6 splenocytes labeling IL-2 Recepter alpha with ab210330 at 0.125 μg (right panel) or 0.125 μg Allophycocyanin Rat IgG1 (left panel). Counterstain: FITC Anti-Mouse CD4.
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