APC Anti-PTP1B + TCPTP antibody [EPR6712]
- RabMAb
- Recombinant
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Rabbit Recombinant Monoclonal PTP1B antibody - conjugated to APC.
View Alternative Names
PTP1B, PTPN1, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B
Product details
Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Protein tyrosine phosphatase 1B (PTP1B) plays a critical role in controlling cell growth differentiation and metabolism. It influences the insulin signaling pathway affecting glucose homeostasis and energy utilization. PTP1B also engages in immune cell signaling and modulation of inflammatory responses. While typically studied independently this phosphatase can also form part of larger molecular complexes that impact broader signaling environments.
Pathways
Protein tyrosine phosphatase 1B acts as a central node in the insulin and leptin signaling pathways. These pathways significantly influence metabolic processes and energy balance with PTP1B modulating key interactions with insulin receptors and leptin receptors. It closely interacts with proteins such as IRS1 and IRS2 which play substantial roles in transmitting signals downstream of insulin action impacting cellular uptake of glucose and lipid metabolism.
Product protocols
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Target data
Additional targets
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com