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AB168746

Anti-APEG1 antibody

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(1 Publication)

Rabbit Polyclonal APEG1 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SPEG.

View Alternative Names

APEG1, KIAA1297, SPEG, Striated muscle preferentially expressed protein kinase, Aortic preferentially expressed protein 1, APEG-1

1 Images
Western blot - Anti-APEG1 antibody (AB168746)
  • WB

Unknown

Western blot - Anti-APEG1 antibody (AB168746)

All lanes:

Western blot - Anti-APEG1 antibody (ab168746) at 1 µg/mL

Lane 1:

APEG1 transfected 293T cell lysate (12.70 KDa) at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Secondary

All lanes:

Goat Anti-Rabbit IgG (H+L), Peroxidase Conjugated secondary antibody at 1/7500 dilution

Predicted band size: 354 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human SPEG.

Q15772

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

APEG1 also known as LRRN6A is a protein involved in cell signaling and adhesion processes. This protein has a molecular mass of approximately 95 kDa. APEG1 is mainly expressed in the nervous system particularly in the neurons. It has an essential role in maintaining cell communication and structural integrity by interacting with other cellular components through its leucine-rich repeat domains.
Biological function summary

APEG1 plays a part in neural development and synapse formation. It contributes to the assembly of synaptic structures aiding neurons in establishing and maintaining effective communication networks. APEG1 is not known to be part of a multi-protein complex but it interacts with other proteins to fulfill its functions in neural tissues.

Pathways

APEG1 is involved in pathways responsible for neural signaling and synaptic plasticity. It often interacts with proteins such as Neuroligin and Neurexin which are key players in synapse formation and maturation. APEG1's role in these pathways supports synaptic function and can influence learning and memory mechanisms.

Research associates APEG1 with neurological conditions such as autism spectrum disorders (ASD) and schizophrenia. Dysfunctional interactions between APEG1 and proteins like Neuroligin have been implicated in these conditions highlighting their role in impaired neural connectivity. Variations in APEG1 expression or function may disrupt synapse formation and stability contributing to the development of these disorders.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
See full target information SPEG

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 24: PubMed36835532

2023

MSX1 Regulates Goat Endometrial Function by Altering the Plasma Membrane Transformation of Endometrial Epithelium Cells during Early Pregnancy.

Applications

Unspecified application

Species

Unspecified reactive species

Beibei Zhang,Zongjie Wang,Kangkang Gao,Rao Fu,Huatao Chen,Pengfei Lin,Aihua Wang,Yaping Jin
View all publications

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