Rabbit Polyclonal APOL2 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human APOL2.
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Publications
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- International journal of oncology 53:266-2742018Inhibition of CD9 expression reduces the metastatic capacity of human hepatocellular carcinoma cell line MHCC97-H.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQing Lin et. al.PubMed 29749468
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.87% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human APOL2. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BQE5
Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Tested | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/50.00000 - 1/100.00000 | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100.00000 - 1/500.00000 | Notes - |
Target data
Function
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
Alternative names
Apolipoprotein L2, Apolipoprotein L-II, ApoL-II, APOL2
Recommended products
Rabbit Polyclonal APOL2 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human APOL2.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.87% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human APOL2. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BQE5
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
APOL2 also known as Apolipoprotein L2 is a protein with molecular mass about 38 kDa. This protein belongs to the apolipoprotein L family and shows expression in various tissues including the pancreas lung and placenta. APOL2 contains lipid-binding domains that enable it to interact with lipids in cellular membranes. It involves in lipid metabolism by aiding the transport of lipids through intracellular compartments.
- Biological function summary
APOL2 contributes to lipid trafficking and cellular lipid homeostasis. It plays a role in the formation of lipid droplets within cells significant for energy storage and regulation. APOL2 does not function alone but often acts in coordination with other proteins involved in lipid metabolism including members of its own family. This association through protein complexes allows for efficient regulation of lipid movement and storage in cells.
- Pathways
Several important pathways intersect with APOL2's functions. It participates in the lipid metabolism pathway which affects energy balance within cells. Another pathway where APOL2 plays a role is the inflammatory response pathway as its expression can influence the response to inflammatory signals. APOL2 shows functional connections with other apolipoprotein family members such as APOL1 through these pathways helping to maintain cellular biochemical equilibrium.
- Associated diseases and disorders
APOL2 relates to cancer and cardiovascular diseases. Aberrant expression of APOL2 can potentially influence cancer progression by impacting cellular lipid metabolism contributing to tumor growth. In cardiovascular diseases its role in lipid metabolism correlates with the regulation of blood lipid levels affecting cardiovascular health. Notably APOL2's function in cardiovascular diseases may interact with APOL1 which has known links to kidney-related disorders and cardiovascular risk factors.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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3 product images
Western blot - Anti-APOL2 antibody (ab196771)
All lanes: Western blot - Anti-APOL2 antibody (ab196771) at 1/500 dilution
Lane 1: COLO cell extracts
Lane 2: HUVEC cell extracts
Lane 3: HUVEC cell extracts with synthesized peptide
Predicted band size: 37 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOL2 antibody (ab196771)
Immunohistochemical analysis of paraffin-embedded Human cervix carcinoma tissue labeling APOL2 with ab196771 at 1/50 dilution. The image on the right is treated with the synthesized peptide.
Immunocytochemistry/ Immunofluorescence - Anti-APOL2 antibody (ab196771)
Immunofluorescent analysis of MCF7 cells labeling APOL2 with ab196771 at 1/100 dilution. The image on the right is treated with the synthesized peptide.
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