Rabbit Polyclonal Apolipoprotein CIV antibody. Suitable for WB, IHC-P and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Mouse Apoc4 aa 1 to C-terminus.
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Publications
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- Proteomics 22:e21000282022Effects of ABCG1 knockout on proteomic composition of HDL in mice on a chow diet and a high-fat diet.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYanxiang Wu,Lianfeng Chen,Ziyan Xie,Chenyu Wang,Jiahao Zhang,Xiaowei YanPubMed 35234362
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.12% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Mouse Apoc4 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q61268
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Mouse | Tested | Tested |
| Rat | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 0.5-2 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info - | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 5-20 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info - | Notes - |
Alternative names
Acl, Apoc4, Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C2-linked, Apolipoprotein C4, ACL
Recommended products
Rabbit Polyclonal Apolipoprotein CIV antibody. Suitable for WB, IHC-P and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Mouse Apoc4 aa 1 to C-terminus.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.12% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Mouse Apoc4 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q61268
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Apolipoprotein CIV (ApoC-IV) is a member of the apolipoprotein family. Structurally it weighs approximately 11 kDa and is expressed mainly in the liver. In terms of function it participates in lipid transport and metabolism acting as a component of lipoprotein particles. ApoC-IV modifies the activity of enzymes involved in lipid metabolism impacting lipid levels in the bloodstream.
- Biological function summary
ApoC-IV plays a significant role in the regulation of triglyceride-rich lipoproteins. It is not part of a larger protein complex but interacts with various components within the lipoprotein transportation system. Its activity affects the breakdown and utilization of lipids influencing lipid homeostasis in the body. Studies suggest that ApoC-IV might have an impact on the efficiency of lipoprotein lipase which is essential for lipid metabolism.
- Pathways
ApoC-IV functions in lipid metabolic processes notably within the triglyceride-rich lipoprotein metabolism pathway. It interacts with other apolipoproteins such as Apolipoprotein CIII (ApoC-III) and Apolipoprotein E (ApoE) which also contribute to lipid regulation in this pathway. These interactions help maintain balance in lipid levels and ensure proper lipid distribution through tissues.
- Associated diseases and disorders
ApoC-IV links to cardiovascular disease and hyperlipidemia. It can influence plasma lipid levels and contribute to lipid imbalances associated with these conditions. ApoC-IV functions alongside proteins like ApoE and ApoB in these diseases where abnormal lipid transport and metabolism can exacerbate disease progression. Understanding its role offers insights into potential therapeutic targets for lipid-related disorders.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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4 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (ab232710)
Formalin-fixed, paraffin-embedded mouse kidney tissue stained for Apolipoprotein CIV using ab232710 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Apolipoprotein CIV antibody (ab232710)
Formalin-fixed, paraffin-embedded mouse liver tissue stained for Apolipoprotein CIV using ab232710 at 20 μg/ml in immunohistochemical analysis. DAB staining.
Western blot - Anti-Apolipoprotein CIV antibody (ab232710)
All lanes: Western blot - Anti-Apolipoprotein CIV antibody (ab232710) at 1 µg/mL
All lanes: Mouse serum
SecondaryAll lanes: HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution
Predicted band size: 15 kDa
Western blot - Anti-Apolipoprotein CIV antibody (ab232710)
All lanes: Western blot - Anti-Apolipoprotein CIV antibody (ab232710) at 1 µg/mL
All lanes: Recombinant mouse Apolipoprotein CIV protein
SecondaryAll lanes: HRP-Linked Guinea pig Anti-Rabbit Ab at 1/2000 dilution
Predicted band size: 15 kDa
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