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AB213161

Anti-ARMC3 antibody

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(1 Publication)

Rabbit Polyclonal ARMC3 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ARMC3 aa 750 to C-terminus conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

Armadillo repeat-containing protein 3, Beta-catenin-like protein, Cancer/testis antigen 81, KU-CT-1, CT81, ARMC3

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-ARMC3 antibody (AB213161)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ARMC3 antibody (AB213161)

Immunofluorescent analysis of A431 cells labeling ARMC3 using ab213161 at a 1/100 dilution in PBS and incubated for one hour at room temperature, followed by secondary antibody incubation, DAPI staining of the nuclei and detection.

Immunocytochemistry/ Immunofluorescence - Anti-ARMC3 antibody (AB213161)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ARMC3 antibody (AB213161)

Immunofluorescent analysis of SMMC7721 cells labeling ARMC3 using ab213161 at a 1/50 dilution in PBS and incubated for one hour at room temperature, followed by secondary antibody incubation, DAPI staining of the nuclei and detection.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Synthetic Peptide within Human ARMC3 aa 750 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q5W041

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ARMC3 also known as Armadillo Repeat Containing 3 acts as a structural protein involved in intracellular processes. This protein weighs approximately 78 kDa and is highly conserved across different species. Expression of ARMC3 is mainly noted in tissues such as the testis and brain indicating its involvement in specific cellular functions within these organs.
Biological function summary

ARMC3 plays a role in cellular structure and signaling. Research indicates that ARMC3 participates in forming protein complexes that assist in signal transduction and cytoskeletal arrangements. These complexes are essential for maintaining cellular integrity and function highlighting the protein's importance in regulating cellular behavior and communication.

Pathways

ARMC3 interacts with other proteins in cytoskeletal organization and cell signaling pathways. It is known to engage in interactions with other structural proteins such as β-catenin which is critical in the Wnt signaling pathway. This engagement suggests its role in facilitating communication between cellular components and impacting cellular responses through modulation of pathway activities.

ARMC3 shows associations with ciliopathies and neurodegenerative diseases. Disruptions in ARMC3 expression or function can lead to developmental disorders affecting cilia structure and function. Additionally ARMC3 interactions with proteins like LRRK2 suggest potential links to Parkinson’s disease where cytoskeletal dynamics play an important role in disease pathology. Understanding the exact contribution of ARMC3 in these contexts remains a significant area of research.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Essential for male fertility and sperm motility (By similarity). During spermatogenesis, promotes the autophagic degradation of excessive ribosomes, providing energy resources for mitochondria and thus ensuring sperm flagellar motility (PubMed : 34428398).
See full target information ARMC3
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:5728 PubMed40593621

2025

HDL-bound S1P affects the subventricular niche and early neuropathological features of Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Byung Jo Choi,Ju Yeon Hong,Min Hee Park,Kang Ho Park,Wan Hui Han,Hee Ji Yoon,Hye Yoon Jung,Kyung Yeol Kim,Sun Ae Lee,Eun Young Lim,Jung Woo Hur,Im-Sook Song,So Yeon Jeon,Min-Koo Choi,Christina Christoffersen,Hee-Jin Kim,Seung Hyun Kim,Edward H Schuchman,Jae-Sung Bae,Hee Kyung Jin
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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