Anti-ATP5G3 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

ATP5G3 plays an important role in the mitochondrial ATP synthase complex also referred to as Complex V part of the electron transport chain. This complex catalyzes the conversion of ADP and inorganic phosphate into ATP using the proton gradient established by the complexes I-IV. ATP5G3 through its mechanical function helps maintain the efficiency of ATP production within cells. Its operation is important for cellular energy supply supporting processes like muscle contraction and biosynthetic reactions.

Pathways

ATP5G3 integrates into the oxidative phosphorylation pathway where it interacts with other subunits of the ATP synthase complex to ensure ATP synthesis. This pathway coordinates with the citric acid cycle (Krebs cycle) which generates the electrons used to establish the proton gradient necessary for ATP production. Proteins such as cytochrome c and NADH dehydrogenase (Complex I) connect with ATP5G3 through their roles in the electron transport chain creating a streamlined flow of electron transfer and energy conversion.