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AB243014

Anti-Attractin antibody [EPR21807-227] - BSA and Azide free (Detector)

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Rabbit Recombinant Monoclonal Attractin antibody. Carrier free. Suitable for sELISA and reacts with Human, Rat samples.

View Alternative Names

KIAA0548, MGCA, ATRN, Attractin, DPPT-L, Mahogany homolog

1 Images
Sandwich ELISA - Anti-Attractin antibody [EPR21807-227] - BSA and Azide free (Detector) (AB243014)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Attractin antibody [EPR21807-227] - BSA and Azide free (Detector) (AB243014)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab263888).

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR21807-227

Isotype

IgG

Carrier free

Yes

Reacts with

Human, Rat

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

ab243014 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human Attractin. The recommended pair for sandwich ELISA is:
Capture: ab243013, Human Attractin Capture Antibody (unconjugated)
Detector: ab243014, Human Attractin Detector Antibody (unconjugated)
The reference range value is 2.8125 - 180 ng/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Attractin also known as ATRN is a multifunctional protein with a molecular weight of approximately 175 kDa. It plays a role in the nervous system and immune functions. Attractin has the ability to bind melanocortins and is expressed in a variety of tissues notably in the brain blood and immune cells. This protein exists both in a membrane-bound form and a soluble form which results from an alternate splicing and shedding process.
Biological function summary

Attractin involves in controlling cell interactions in the immune system. It forms part of complexes on cell surfaces that affect leukocyte adhesion and migration. This protein modulates T-cell interactions which influences immune responses and facilitates cell communication. It may also have roles in neuroendocrine signaling suggesting its involvement in the communication between neurons and endocrine tissues.

Pathways

The presence of Attractin influences cell signaling pathways that regulate immune responses and cell adhesion. It interacts with the melanocortin pathway which involves melanocortin receptors and is critical for regulating inflammatory responses. Attractin also associates with proteins such as chemokines that mediate cell signaling involved in immune response and neuroinflammation pathways.

Attractin has connections to neurological and autoimmune disorders. Mutations in the Attractin gene link to neurological conditions such as seizure disorders where it contributes to abnormal neuron signaling. Additionally there is a relationship with autoimmune disorders where dysregulation of Attractin function can lead to enhanced leukocyte activity. Through its role in these conditions Attractin interfaces with other proteins like CD44 in impacting immune system dysfunction.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).
See full target information ATRN
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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