JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB51586

Anti-Bacillus thuringiensis CRY1Ab Toxin antibody

Be the first to review this product! Submit a review

|

(6 Publications)

Rabbit Polyclonal CR1AB antibody. Carrier free. Suitable for IP, ELISA, WB and reacts with Bacillus thuringiensis samples. Cited in 6 publications.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Bacillus thuringiensis

Applications

IP, WB, ELISA

applications

style
left-column

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB307727

Anti-ALP antibody [EPR27191-14] - BSA and Azide free

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALP antibody [EPR27191-14] - BSA and Azide free (AB307727)

  • 0
  • 0
Primary Antibodies

AB3649

Anti-Mucin 5AC antibody [45M1]

BOND RX™ Validated|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mucin 5AC antibody [45M1] (AB3649)

  • 5
  • 8
Primary Antibodies

AB69152

Anti-CXorf21 antibody

Western blot - Anti-CXorf21 antibody (AB69152)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Bacillus thuringiensis": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.3 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Bacillus thuringiensis CRY1Ab toxin also referred to as CRY1Ab protein is a crystal protein with a molecular mass of approximately 130 kDa. It is produced as an inactive protoxin in Bacillus thuringiensis and becomes active upon ingestion by target insect larvae. Once ingested the alkaline conditions of the insect gut activate the CRY1Ab toxin by proteolysis. This activation allows CRY1Ab to bind to specific receptors in the insect midgut epithelium leading to pore formation and cell lysis which ultimately kills the insect.
Biological function summary

The CRY1Ab toxin acts as an insecticidal agent targeting Lepidoptera orders such as the European corn borer. It functions by disrupting the gut cells of susceptible insects which results in nutrient absorption issues and lethal effects. CRY1Ab proteins do not belong to any known protein complexes but exhibit remarkable efficacy independently allowing them to serve as a potent biological control tool in agriculture.

Pathways

The CRY1Ab toxin integrates into the defense mechanisms of transgenic crops. It aligns with insect resistance pathways by expressing the CRY1Ab protein to combat pests directly. This mechanism involves multiple receptor proteins like cadherin which assist the binding process of CRY1Ab in the insect gut. This specific interaction ensures that CRY1Ab efficiently participates in safeguarding crops by reducing pest-related damage.

CRY1Ab toxin does not directly associate with human or mammalian diseases due to its specificity to insect gut conditions. However there are discussions about its environmental impact and potential allergenicity in relation to food safety. CRY1Ab might influence agricultural bioengineering efforts mainly in the context of pest control management strategies rather than human medical conditions creating ties with proteins related to pest resistance mechanisms in biotechnology.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information Bacillus thuringiensis CRY1Ab Toxin
style
left-column

Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Biotech (Basel (Switzerland)) 14: PubMed40981368

2025

Translocation of Insecticidal Bt Protein in Transgrafted Plants.

Applications

Unspecified application

Species

Unspecified reactive species

Arisa Ando,Hitomi Ohkubo,Hisae Maki,Takumi Nishiuchi,Takumi Ogawa,Tomofumi Mochizuki,Daisaku Ohta,Hiroaki Kodama,Taira Miyahara

Frontiers in physiology 15:1484489 PubMed39534858

2024

Cry1Ac toxin binding in the velvetbean caterpillar : study of midgut aminopeptidases N.

Applications

Unspecified application

Species

Unspecified reactive species

M D Lanzaro,I Padilha,L F C Ramos,A P G Mendez,A Menezes,Y M Silva,M R Martins,M Junqueira,F C S Nogueira,C D AnoBom,G M Dias,F M Gomes,D M P Oliveira

PloS one 12:e0178754 PubMed28582405

2017

Laboratory evaluation of transgenic Populus davidiana×Populus bolleana expressing Cry1Ac + SCK, Cry1Ah3, and Cry9Aa3 genes against gypsy moth and fall webworm.

Applications

Unspecified application

Species

Unspecified reactive species

Liping Ding,Yajuan Chen,Xiaoli Wei,Mi Ni,Jiewei Zhang,Hongzhi Wang,Zhen Zhu,Jianhua Wei

Biotechnology for biofuels 7:68 PubMed24808924

2014

Production of marker-free transgenic Jatropha curcas expressing hybrid Bacillus thuringiensis δ-endotoxin Cry1Ab/1Ac for resistance to larvae of tortrix moth (Archips micaceanus).

Applications

WB

Species

Rice

Keyu Gu,Huizhu Mao,Zhongchao Yin

PloS one 9:e92189 PubMed24739804

2014

Multi-method approach for characterizing the interaction between Fusarium verticillioides and Bacillus thuringiensis subsp. Kurstaki.

Applications

IF

Species

Unspecified reactive species

Liliana O Rocha,Sabina Moser Tralamazza,Gabriela M Reis,Leon Rabinovitch,Cynara B Barbosa,Benedito Corrêa

Applied and environmental microbiology 78:6466-74 PubMed22773626

2012

Weak transcription of the cry1Ac gene in nonsporulating Bacillus thuringiensis cells.

Applications

WB

Species

Unspecified reactive species

Hui Yang,Pinshu Wang,Qi Peng,Rong Rong,Chunxia Liu,Didier Lereclus,Jie Zhang,Fuping Song,Dafang Huang
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com