AB135907

Anti-BAI1 antibody

Name: Anti-BAI1 antibody (ab135907) | Abcam
Brand: Abcam Limited
SKU: AB135907
Price: 535 USD
Availability: InStock
Rating: 5 (2 reviews)

(2 Reviews)

(6 Publications)

Rabbit Polyclonal BAI1 antibody. Suitable for WB, IHC-P, IHC-Fr and reacts with Mouse, Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human ADGRB1 aa 650-750.

View Alternative Names

BAI1, ADGRB1, Adhesion G protein-coupled receptor B1, Brain-specific angiogenesis inhibitor 1

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAI1 antibody (AB135907)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAI1 antibody (AB135907)

Immunohistochemical analysis of paraformaldehyde-fixed, 0.3% Triton X-100 permeabilized paraffin-embedded mouse hippocampus tissue labeling BAI1 with ab135907 at 1/50 dilution,followed by Goat Anti-Rabbit IgG (HRP) at 1/500 dilution.

Unknown

Western blot - Anti-BAI1 antibody (AB135907)

All lanes:

Western blot - Anti-BAI1 antibody (ab135907) at 1/500 dilution

All lanes:

Huvec cell lysate at 30 µg

Predicted band size: 174 kDa,66 kDa,85 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

IHC-Fr, WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human ADGRB1 aa 650-750. The exact immunogen used to generate this antibody is proprietary information.

O14514

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography.

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed : 24509909). Also mediates the binding and engulfment of Gram-negative bacteria (PubMed : 26838550). Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed : 26838550). In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PubMed : 24509909). Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner (PubMed : 23782696). Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity). Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity). Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PubMed : 11875720).. Vasculostatin-120. Inhibits angiogenesis in a CD36-dependent manner.. Vasculostatin-40. Inhibits angiogenesis.

See full target information ADGRB1

style

left-column

Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Thoracic cancer 12:1673-1680 PubMed33934543

2021

BAI1 nuclear expression reflects the survival of nonsmoking non-small cell lung cancer patients.

Applications

Unspecified application

Species

Unspecified reactive species

Hyo Jung An,Sung Hwan Kim,Jung Wook Yang,Min Hye Kim,Hye Jin Baek,Kyeong Hwa Ryu,Kyung Nyeo Jeon,Chang Sup Lee,Jun Young Choi,Dae Hyun Song

eLife 9: PubMed32894219

2020

Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair.

Applications

Unspecified application

Species

Unspecified reactive species

Francisca Benavente,Katja M Piltti,Mitra J Hooshmand,Aileen A Nava,Anita Lakatos,Brianna G Feld,Dana Creasman,Paul D Gershon,Aileen Anderson

Molecular medicine reports 14:1553-9 PubMed27356780

2016

Biological effects of eukaryotic recombinant plasmid pReceiver-M61-BAI-1 transfection on T24 cells and HUVECs.

Applications

Unspecified application

Species

Human

Da-Wei Tian,Hai-Long Hu,Yan Sun,Yang Tang,Ming-De Lei,Li-Wei Liu,Rui-Fa Han,Chang-Li Wu

Frontiers in genetics 6:334 PubMed26635870

2015

Genome-Wide Screening of mRNA Expression in Leprosy Patients.

Applications

IHC

Species

Human

Andrea de Faria F Belone,Patrícia S Rosa,Ana P F Trombone,Luciana R V Fachin,Cássio C Guidella,Somei Ura,Jaison A Barreto,Mabel G Pinilla,Alex F de Carvalho,Dirce M Carraro,Fernando A Soares,Cleverson T Soares

Molecular medicine reports 12:4522-4529 PubMed26129954

2015

Expression of brain‑specific angiogenesis inhibitor‑1 and association with p53, microvessel density and vascular endothelial growth factor in the tissue of human bladder transitional cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Dawei Tian,Hailong Hu,Yan Sun,Yang Tang,Mingde Lei,Liwei Liu,Ruifa Han,Changli Wu

FASEB journal : official publication of the Federa 28:2214-24 PubMed24509909

2014

Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells.

Applications

IHC-Fr

Species

Human

Soumita Das,Arup Sarkar,Kieran A Ryan,Sarah Fox,Alice H Berger,Ignacio J Juncadella,Diane Bimczok,Lesley E Smythies,Paul R Harris,Kodi S Ravichandran,Sheila E Crowe,Phillip D Smith,Peter B Ernst

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-BAI1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BAI1 antibody (AB135907)

Western blot - Anti-BAI1 antibody (AB135907)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (6)

Complementary Products

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Product promise