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AB317423

Anti-BarX1 antibody [S01-3A3]

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Rabbit Recombinant Monoclonal BARX1 antibody. Suitable for WB and reacts with Human, Rat, Chinese hamster samples.

View Alternative Names

Homeobox protein BarH-like 1, BARX1

1 Images
Western blot - Anti-BarX1 Antibody [S01-3A3] (AB317423)
  • WB

Supplier Data

Western blot - Anti-BarX1 Antibody [S01-3A3] (AB317423)

All lanes:

Western blot - Anti-BarX1 Antibody [S01-3A3] (ab317423) at 1/1000 dilution

Lane 1:

HeLa cell lysate

Lane 2:

CHO-K1 cell lysate

Lane 3:

C6 cell lysate

Lane 4:

Ramos cell lysate

Predicted band size: 28 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

S01-3A3

Isotype

IgG

Carrier free

No

Reacts with

Human, Rat, Chinese hamster

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Chinese hamster": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Product details

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

BarX1 also known as BarH-like homeobox 1 is a transcription factor with a molecular mass of approximately 29 kDa. It is part of the Bar family of proteins which play essential roles in development. BarX1's primary expression occurs in the central nervous system and mesenchymal tissues during embryonic development. In adults BarX1 shows limited expression in specific tissues such as the stomach where it may serve various regulatory functions.
Biological function summary

BarX1 functions in the development of multiple organ systems particularly in teeth and stomach. It acts by influencing the differentiation and proliferation of cells during the formation of these structures. BarX1 is known to be part of a regulatory complex that controls the expression of genes critical for morphogenesis and tissue specification. Its interaction with other homeobox proteins further expands its impact on development.

Pathways

BarX1 interacts in key developmental signaling pathways such as Wnt and Hedgehog. These pathways play significant roles in development influencing cell fate and patterning. BarX1's interaction with proteins like beta-Catenin in the Wnt pathway helps modulate the activity of downstream genes necessary for development. By participating in these pathways BarX1 helps maintain the balance between cell proliferation and differentiation.

Dysregulation of BarX1 expression has been linked to conditions such as gastric cancer and tooth agenesis. In gastric cancer abnormal BarX1 levels can disrupt normal gene expression leading to uncontrolled cell growth and tumor development. Connections also exist between BarX1 and E-cadherin; alterations in this interaction can influence cancer progression. In tooth agenesis insufficient BarX1 activity can impair the formation of dental tissues resulting in missing teeth. Understanding these associations aids in developing targeted therapeutic interventions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.
See full target information Homeobox protein BarH-like 1

Additional targets

BarX1,RarX1
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Product promise

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