Anti-Basophils antibody [2D7]
4
(6 Reviews)
|
(7 Publications)
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Basophils play an important role in immune response regulation particularly in allergic reactions and parasitic infections. Basophils do not form part of a complex but interact dynamically with other immune cells. Released substances from their granules contribute to inflammation and help control the intensity of the immune response. Basophil markers including 2D7 help identify these cells and examine their function in immunological studies.
Pathways
Basophils are critical players in the Th2 immune response pathway and the allergic inflammation pathway. In the Th2 response basophils secrete cytokines that promote the activation and differentiation of T-helper 2 (Th2) cells. They relate to other proteins like IL-4 and IL-13 which are significant in the mediation of allergic responses. Basophils contribute to the recruitment and activation of other immune cells like eosinophils through the secretion of cytokines and chemokines.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Publications (7)
Recent publications for all applications. Explore the full list and refine your search
The Journal of dermatology 50:927-930 PubMed36651089
2023
Applications
Unspecified application
Species
Unspecified reactive species
Journal of the American Academy of Dermatology 83:53-62 PubMed31351883
2019
Applications
Unspecified application
Species
Unspecified reactive species
Journal of gastroenterology 53:449-460 PubMed28921377
2017
Applications
IHC-P
Species
Human
PloS one 9:e111352 PubMed25361058
2014
Applications
IHC
Species
Human
Journal of clinical pathology 59:396-402 PubMed16461568
2006
Applications
Unspecified application
Species
Unspecified reactive species
The Journal of allergy and clinical immunology 117:626-34 PubMed16522463
2006
Applications
Unspecified application
Species
Unspecified reactive species
The Journal of allergy and clinical immunology 101:354-62 PubMed9525452
1998
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com